notes from quesmed Flashcards
what condition is a risk factor of sub arachnoid haemorrhage
PKD polycystic kidney disease
PKD is caused by
autosomal dominant caused by mutation on chromosome 16
autosomal recessive caused by mutation on chromosome 9
deformities seen in late stage severe rheumatoid
swan neck deformity
boutonnieres
ulnar deviation
z thumb deformity
extraglandular features of sjogrens
systemic upset
arthritis
raynauds
pupura
skin ulcers
interstitial lung disease
renal disease
neurological disease eg seizures
antidepressant therapy should be continued for how long after remission
6 months
symptoms of lithium toxicity
diarrhoea
vomiting
abdo pains
polyuria
polydipsia
fine tremor
drowsiness
weakness
severe=
agitation
slurred speech
seizures
renal failure
tachycardia
confusion
delirium
death
what is gilberts syndrome
autosomal recessive condition resulting in defective bilirubin conjugation
jaundice, often precipitated by stress or an infection
isolated hyperbilirubinaemia (unconjugated)
no treatment or managment
what is wilsons disease
autosomal recessive genetic condition
excessive accumulation of copper in the body tissues, particularly in the liver.
mutations in the Wilson disease protein gene on chromosome 13. this copper transporting gene is important in removing excess copper from body via liver. copper is excreted in bile
teenagers and young adults
liver problems
neuro or psych problems
kayser fleischer rings around eyes
haemolytic anaemia
antibodies in SLE
most specific markers for SLE are anti-dsDNA antibodies and anti-Sm (anti-smith) antibodies.
what does CHADS VASC score do and what does it involve
risk of stroke in a fib
age- 65-74 is 1 and > 75 is 2
sex. 1 for female
CHF history
hypertension
stroke history +2 for this
vascular disease history
diabetes
what do u use for focal seizures treatment
lamotrigine
what is first line for diabetics with hypertension
ramipril ACE inhibitor
most common cause of infectious exacerbation of COPD
haemophilus influenzae
