Notes chapter 17 Flashcards
Millieqivalent ?
Refer to the concentration electronically certain volume of solution express as milliequivalent per liter (mEq/L)
Body surface area is defined ? .
as the total area exposed to the outside environment
dimensional analysis?
method (also called factor labeling or the label factor method )
Dimensions analysis following three ?
1.Drug label
2.Conversion
3.Drug order
PROBLEM: The physician orders 40 mg of furosemide(Lasix). An ampule (small glass container that usually contains a single dose of a solution) of furosemide labeled “Lasix 20 mg/mL” is available.?
Example 1 pg 430
PROBLEM: The physician orders 15 mg of diazepam(Valium). Valium tablets that contain 5 mg / tablet are available.?
Example 2 430
Order calls for acetaminophen (Tyleno) gr xv, PO, prn (15 grains, by mouth, as needed). AVAILABLE:200 tablets -325MG each ?
Example 3
PROBLEM: The average adult dose of a medication is 25 mg. What is an appropriate dose of this medication for a child who weighs 40 Ib?
Example 4
PROBLEM: The average adult dose of a medication is 25 mg. What is an appropriate dose of this medication for a child who is 22 months of age?
example 5
PROBLEM: Trey, an 8-year-old, weighs 60 lb and is 51 inches tall. His body surface area (as determined with the nomogram in Fig. 17.1) is 1.0. If an adult dose is 50 mg, how many milligrams should Trey receive?
example 6
Pharmacology?
is the study of drugs (medications) and their action on the living body.
Lethal dose?
The amount of a drug that causes death
A metabolite?
is a substance produced by metabolic action,which results in the breakdown of the drug
A drug that builds up in the body is said to have a cumulative?
(increasing by increments)
-effect, which sometimes leads to toxic (harmful) or even lethal (deadly) outcomes tor the patient
stat?
-are planned to manage an emergency patient conditions
-they are to be complete before order
-is one time only dose
It is important for the nurse to be familiar with therapeutic ?
(beneficial) dosages of frequently used drugs to administer doses of medication competently to patient ?book
When one drug alters the action of another drug, it is called?
a drug interaction (a modification of the effect of a drug when administered with another drug).
When one drug increases the action or the effect of another drug, it is called ?
potentiation of the drug, or synergism.
Compatibility?
-is the quality or state of harmonious coexistence.
-Drug compatibility is the ability to administer medications together easily without any difficulty for the patient.
A drug that produces a predictable response at the intended site of action is called?
agonist
(its tell the cell to bind to receptor increase the function bind receptor /attract and encourage molecules bind cell)
is a drug that blocks the action of another drug.
- drugs are used to counteract the effects of a previously given drug
. Anatagonist
(-anatagonist is going to bind to the receptor prevent or block any molecules bond with receptor (prevent something to happen)
-A common antagonist prescribed is naloxone hydrochloride (Narcan) It is given when a person has received too much of an opioid medication,such as morphine sulfate.
An idiosyncratic?
reaction to a drug results from the individual’s unique hypersensitivity to it.
A reduced response to a drug over time is called a drug ?
tolerance
-The patient who has developed tolerance to a drug requires a larger dose of the drug to achieve the same effect that a smaller therapeutic dose once produced.
adverse drug reaction ?
(a harmful, unintended reaction to a drug administered at a normal dosage), drug hypersensitivity, or intolerance to the drug
Use the resource to determine the therapeutic dosage?
- indications for use of the drug,
-contraindications (conditions in which the drug should not be used), -
-side effects,
-available formulations and routes of administration,
-generic and trade names, and information regarding how to manage overdoses.
The following factors may affect how patients respond to medication?
-age
-weight
-gender (Women tend to have a higher percentage of body fat than men. Because some drugs are fat soluble ,women with high body fat percentage)
-Ethnicity
-physical conditions
-psychological status
-environment temperature
-amount of food in the stomach
-route of administration
Influence of Aging on Drug Actions in Older Adults Oral Cavity ?
-Loss of elasticity in oral mucous,which becomes dry and easily abraded
Influence of Aging on Drug Actions in Older Adults Esophagus?
Delayed esophageal clearance because of weakened contractions and failure of lower esophageal sphincter to relax
Influence of Aging on Drug Actions in Older Adults Stomach?
Decrease in gastric acidity and peristalsis
Influence of Aging on Drug Actions in Older Adults’ Large Intestines?
Reduced colon muscle tone; loss of defecation reflex; decreased intestinal blood flow
Influence of Aging on Drug Actions in Older Adults Skin and Vascular System ?
Reduced subcutaneous skinfold thickness in extremities (less body fat); reduced elasticity in skin and vascular system; increased fragility of blood vessels
Influence of Aging on Drug Actions in Older Adults Liver?
Reduced liver size; decline in hepatic blood flow
Influence of Aging on Drug Actions in Older Adults Kidneys?
Reduced glomerular filtration; decreased tubular function and renal blood flow
Drugs enter through the central route?
Are absorbed within GI tract
Forms of enter medications Often mixed with a liquid (diluent) before administration?
Powers
Round, solid drug form that must break down into solution form (dissolution) in the stomach?
Pills