Notes #3 Flashcards
Miotic Recombination
the combination of parental genes not found in the parent organisms through mitosis (often as a result of radiation)
Ionizing Radiation
(x-rays, radioactivity) ionize molecules at random throughout cells (severe damage breaks covalent bonds)
U.V. Radiation
absorbed by specific molecules
“Target”
cell components most sensititve to damage (DNA)
Ionizing Radiation (Damage)
separates or breaks double-stranded structure of DNA (no replication)
U.V. Radiation (Damage)
selectively absorbed by purine and pyrimidine bases (more concentrated radiation)
U.V. rays form ______.
dimmers (T-T, C-C, T-C covalent bonds that prevent cell replication)
Radiation repair
before too much O2 and O3 production —–> greater radiation
Photoreactivation (repair)
when U.V. damaged cells are exposed to visible light. They use the energy to produce enzymes that reverse the formation of dimmers
Excision Repair
sequence of events that remove damaged DNA, then resynthesize the missing portion (mutations often occur during messed up resynthesis of DNA)
Lethal effects of radiation
DNA damaged not repaired before DNA replication (cell dies)
Reproductive Death
When a cell can divide to form viable, but mutated offspring
Metabolic Death
when cells are killed outright