Nornal Ageing, Dementia, Nutrition Flashcards
When does care for the elderly begin
~70 but not consistent
Descrbe changes to lung compliance eith age
Lung and chest wall compliance decrease with advancing age. Total lung capacity (TLC), Forced Vital Capacity (FVC), Forced Expiratory Volume in 1 second (FEV1) and Vital Capacity are all reduced as people age.
These changes occur as a result of reduction in elastic support of the airways and leads to increased collapsibility of alveoli and terminal conducting airways.
What are teh clinicalconsequences of the ageing of the respiratory system
Atelectasis, pulmonary emboli and pneumonia are common post-operative complications in the elderly.
• These complications are increased in smokers, patients with chronic chest disease and those undergoing abdominal or thoracic surgery.
Melnutrition and immunodeficiency can exacerbate this
What are the changes to he oropharynx with age
• With advancing age, loss of elastic tissue around the oropharynx can lead to collapse of the upper airway. Sleep or sedative states may result in partial or complete obstruction of the airway
• A progressive increase in the number of episodes of arterial desaturation during sleep occurs with advancing age.
If treating what opiate - depress cns function - older patients will be more prone to worse arterial desaturation at night,, they may not be monitored at night and at home
Descrive ageing and pk
Elderly patients have an increased sensitivity to CNS depressant drugs and so drug doses need to be modified accordingly.
Patients have reduced hepatic and renal function leading to slower metabolism and elimination of drugs.
Takes longer for drug to take effect, takes longer for it to be eliminated. Do not give elderly same dosage as younger adult. Wait for the response before you give more
Desribe skin changes in the elderly
Elderly patients tend to have thin skin and fragile subcutaneous blood vessels and therefore patients tend to bruise easily. Achieving and securing venous access can be difficult
Most older patients have fragile skin prone to bruising. Harder to insert cannula. Dermis reduced. Iv fluid can leak around site of cannula causeing pain swelling and infection
Describe changes to blood vessels n the elderly
• Large and medium sized vessels become less elastic and therefore become less compliant with age.
• This results in raised systemic vascular resistance and hypertension, which in turn may lead to left ventricular strain and left ventricular hypertrophy
Less compliance of large and medium sized vessels
LV has to pump against resistance
Hypertrophy
Describe ageing of the conducting cells
- Cardiac conducting cells decrease in number making heart block, ectopic beats, arrhythmias and atrial fibrillation more prevalent.
- Since atrial contraction contributes approximately one third of the volume towards normal ventricular filling, patients with atrial fibrillation suffer a reduction in cardiac output of about 30%.
Describe changes to tone in periods of stress
Change tone in periods of activity - vessels are redistributing flow to areas that need it most. Eed vascular tone to keep by stable when stand up. In older patients - coziness and falls. Or in activity or stress - cannot redirect blood flow as easily as someone who si younger
What are the changes to co with age
Cardiac output falls by 3% per decade which is due to reduced stroke volume and ventricular contractility.
The reduction in cardiac output with age increases the arm-brain circulation time for drugs and means intravenous anaesthesia is achieved more slowly and with reduced doses of anaesthetic agent.
Elderly people - mroe friar. Less finely tune peripheral vascular response. Drop co by 1/3. They may collapse.
Desribe pharmacology in the elderly
Reduced cardiac output results in delayed onset of intravenous anaesthesia.
Reduced total body water and increased adipose tissue leads to an altered volume of distribution of some drugs.
Plasma proteins are reduced resulting in decreased protein binding and increased free drug availability.
What are changes to gfr in the elderly
- Glomerular filtration rate is thought to decrease by 1% per year over the age of 20 years due to a progressive loss of renal cortical glomeruli.
- A reduction in renal perfusion secondary to reduced cardiac output and atheromatous vascular disease leads to a decline in renal function.
What other factors in the elderly could lead to effects to the renalsystem
- In addition diabetes mellitus is increasingly common, as is the use of nephrotoxic drugs such as non-steroidal anti-inflammatory drugs (NSAID’s) and angiotensin converting enzyme inhibitors (ACE inhibitors).
- Prostatism in males can lead to obstructive nephropathy and dehydration is common in the elderly especially during illness
Describe changes to cvs in the elderly
Many conditions can exacerbate the progress but will happen with age anyway
• Cerebrovascular disease is common in the elderly secondary to diffuse atherosclerosis and hypertension.
• Neuronal density is reduced by 30% by the age of 80 years.
Describe endocrine and metabolic effects of ageing
The basal metabolic rate falls by 1% per year after the age of 30. Fall in metabolic activity and reduced muscle mass may cause impaired thermoregulatory control.