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YEAR 2 - Applied Physiology & Pharmacology > Normal values for physiologically important parameters > Flashcards

Normal values for physiologically important parameters Flashcards

1
Q

What are the intracellular and extracellular concentrations (and ranges) for sodium ions?

A
  • Extracellular: 140mM (range: 135-145mM)
  • Intracellular: 5-15mM
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2
Q

What are the intracellular and extracellular concentrations (and ranges) for potassium ions?

A
  • Extracellular: 4mM (3.5-5mM)
  • Intracellular: 140mM
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3
Q

What are the intracellular and extracellular concentrations (and ranges) for calcium ions?

A
  • Extracellular: 2.4mM (2.12-2.62mM) -> nb that only half of extracellular calcium is present as free calcium/able to contribute to the concentration.
  • Intracellular: 0.1uM
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4
Q

What are the intracellular and extracellular concentrations (and ranges) for chloride ions?

A
  • Extracellular: 100mM (95-105mM)
  • Intracellular: Less than extracellular, but can vary widely from tissue to tissue.
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5
Q

What are the intracellular and extracellular concentrations (and ranges) for bicarbonate ions?

A
  • Extracellular: 25mM (22-29mM)
  • Intracellular: 10-20mM (varies according to intracellular pH)
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6
Q

What are the intracellular and extracellular concentrations (and ranges) for hydrogen ions (protons)?

A
  • Extracellular: 40nM (pH = 7.4)
  • Intracellular: 50-100nM (pH = 7.0-7.3)
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7
Q

What is the range for plasma glucose (fasting)?

A

4-6mM

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8
Q

What is the value for plasma osmolarity?

A

290 mOsm

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9
Q

What is the value for arterial partial pressure of O2?

What is the range?

A

90mmHg (12kPa)

80-100mmHg (11-13kPa)

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10
Q

What is the value for arterial partial pressure of CO2?

What is the range?

A

40mmHg (5.3kPa)

35-45mmHg (4-6kPa)

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11
Q

What is the value for arterial blood pH?

A

pH 7.4 (range: 7.35-7.45)

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12
Q

What is the value for glomerular filtration rate (GFR)?

A

125ml/min

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13
Q

What is the range of values for urine osmolarity?

A

50-1200mOsm

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14
Q

What are the values for systemic arterial blood pressure?

A

120/80 (systolic/diastolic)

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15
Q

What are the values for pulmonary arterial blood pressure?

A

20/10mmHg (systolic/diastolic)

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16
Q

What is the value for resting cardiac output?

A

5L/min

17
Q

What is the value for basal oxygen consumption?

A

250ml/min

18
Q

What is the value for normal ventilation at rest?

A

6 L/min

19
Q

What is the value for alveolar ventilation at rest?

A

4L/min

20
Q

What is the range for normal resting heart rate?

A

60-100bpm

21
Q

For the average 70kg man, what is the volume of the total body fluid compartment?

A

42L

22
Q

For the average 70kg man, what is the volume of the extracellular body fluid compartment as:

  1. Total?
  2. Plasma?
  3. Interstitial fluid?
  4. Transcellular fluid?
A
  1. 14L (roughly 1/3 of total)
  2. 3L
  3. 10L
  4. 1L
23
Q

For the average 70kg man, what is the volume of the intracellular body fluid compartment?

A

28L (roughly 2/3 of total)

24
Q

What is the normal value for a haematocrit?

A

45%

25
Q

What is the normal cell count of RBCs/erythrocytes?

A

5x10^12 cells/L

26
Q

What is the normal cell count of WBCs/leucocytes?

A

~ 7x10^9 cells/L

27
Q

What is the usual differential count of neutrophils compared to the entire complement of WBCs?

A

40-70%

28
Q

What is the usual differential count of lymphocytes compared to the entire complement of WBCs?

A

20-40%

29
Q

What is the usual differential count of monocytes compared to the entire complement of WBCs?

A

~6%

30
Q

What is the usual differential count of eosinophils compared to the entire complement of WBCs?

A

~3%

31
Q

What is the usual differential count of basophils compared to the entire complement of WBCs?

A

<1%

32
Q

What is the normal cell count of platelets?

A

1.5M-4.5M cells/L

33
Q

What is the normal value of CO2 production at rest?

A

200ml/min [CHECK]

YEAR 2 - Applied Physiology & Pharmacology (11 decks)

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