Normal Flora Flashcards
importance of normal flora
protective
pathogenic
nutritional- vitamin K
overgrowth can cause fat malabsorption and vitamin b12 deficiency
aerobes or facultative bacteria in mouth
viridans streptococci
neisseria
diphtheroids
s. epidermidis
viridans streptococci
gram pos cocci
most common cause of subacute bacterial endocarditis
thrive on sugar
nessieria species
gram neg diplococci
neisseria meningitidis inhabits nasopharynx and causes meningitis
diphtheroids
gram pos rods
most common contaminants in blood cultures
s. epidermidis
gram pos cocci
another common contaminant of blood culture
coagulase neg
role of normal aerobic flora in disease
1 if eliminated by antibiotics, can be colonized by pathogens
2 some individuals have pathogens in their mouths
3 can be colonized by e coli or kleb in hospitalized
anerobes in the oral cavity and drug sensitivities
fusobacterium- penicillin sensitive
prevotella- penicillin sensitive
peptostreptococcus- peniccilin sensitive
actinomyces
do not extend into trachea
cause peridontal infections and aspiration pneumonia
normal stomach flora
none- acid
normal upper small intestine
generally sterile, but can cause disease if stasis occurs
normal terminal ileum flora
gram neg enterobacteria- e coli, enterobacter
anaerobes- bacteroides fragilis
normal bacteria in large intestine/ feces
bacteroides- gram neg anaerobic rods
form ammonia, acid, and gas
bacteroides fragilis- resistant to penicillin, causes intraabdominal infections
treated w/ clindamycin, cefoitin, or metronidazole
bifidobacterium- gram pos rods- non pathogenic
lactobacilli- gram pos rods- produce lactic acid and keep pH low
clostridium
enterococcus
establishment of normal intestinal flora
sterile at birth
colinzed w/in hours and looks normal by the time infant is bottle fed
maintenance of intestinal flora
oxygen level and pH
administration of antibiotics
presence of nutrition provided by other bacteria
metabolic activities of normal flora
bile acid deconjugation- abnormal growth in upper intestine will impair fat absorption
provides ammonia to blood
conversion of bile pigments (bilirubin to urobilin and stercobilin)
ferment undigested carbs and drop pH
bacteroidetes found in lean individuals and firmicutes in obese individuals