Anaerobes Flashcards

1
Q

common features of anaerobic infections

A

1 many abcesses originate from native flora, of which anaerobes are a major part

2 anaerobic are characterized by foul smelling discharge, gas, and necrotic tissue

3 predisposing conditions- aspiration, bowel surgery, dental hygiene, abortion, bites, trauma, malignancy

4 occur deep in tissues

5 almost all anaerobic infections are mixed w/ other anaerobes or microaerophilic organisms

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2
Q

what bacteria cause CNS infections

A

anaerobes
oral anerobes

aerobes
Staphylococcus aureus
Streptococcus

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3
Q

what bacteria cause chronic otitis media

A

anaerobes
oral anaerobes

aerobes
pseudomonas a
staphylococcus

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4
Q

what bacteria cause dental infections

A
anaerobes
prevotella
fuscobacterium nucleatum
peptostreptococcus
actinomyces

aerobes
staphylococcus
streptococcus

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5
Q

what bacteria cause lung infections

A

anaerobes
prevotella
fusobacterium
peptostreptococcus

aerobes
staphylococcus
streptococcus
enterobactericeae

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6
Q

what bacteria cause peritonitis

A
anaerobes
bacteroides fragilis
fusobacterium
peptostreptococcus
clostridium
aerobes
e coli
proteus
klebsiella
pseudomonas a.
group d streptococcus
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7
Q

what bacteria cause liver and subphrenic abscesses

A

anaerobes
colonic flora

aerobes
staphylococcus
enterobactericeae
pseudomonas

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8
Q

what bacteria cause OBGYN infection

A

anaerobes
colonic flora

aerobes
group B streptococcus
e coli
staphylococcus

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9
Q

what bacteria cause perirectal abscesses

A

anaerobes
colonic flora

aerobes
staphylococcus

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10
Q

what bacteria cause skin and muscle infections

A

anerobes
clostridium

aerobes
staphylococcus
streptococcus
e coli

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11
Q

most anaerobic infections are caused by endogenous flora, and can be predicted by knowledge of normal anerobic flora located near the site of infection

A

ok

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12
Q

importance of the diaphragm

A

bacteroides fragilis is pencillin resistant and found below the diaphragm

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13
Q

oral infections

A

penicillin sensitive, gram positive cocci

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14
Q

intraabdominal infections

A

penicllin resistant, gram negative rods

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15
Q

media needed for anerobic growth

A

thioglycollate broth

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16
Q

anaerobic gram negative rods

A

bacteroides fragilis
prevotella melaninogenicus
fusobacterium

17
Q

bacteroides fragilis

A

most common anaerobic gram neg rod

found in large numbers in large intestine

resists bacteriocidal action of bile

causes septicemia

penicillin resistant

capsule is major virulence factor

18
Q

prevotella melaninogenicus

A

anaerobic gram neg rod

common in oral infectinos, serious agent of periodontal disease

sensitive to peniccilin

black pigment formed on blood agar plate

19
Q

fusobacterium

A

gram negative rods

have tapered ends (needle shape) and very thin

sensitive to penicillin and oxygen sensitive

important in oral infections, pulmonary infections, and abdominal infections

20
Q

nonspore forming gram pos rods

A
bifidobacterium
corynebacterium
lactobacillus
actinomyces
clostridia
21
Q

bifidobacterium

A

gram pos rods

found in large numbers in normal large intestine

does not cause infections, used in probiotics

22
Q

corynebacterium

A

gram pos rod

causes diptheria, otherwise ot usually involved in infections

23
Q

lactobacillus

A

gram pos rod

normal flora of intestine and vagina

non pathogen

important for maintaining pH that is productive

24
Q

actinomyces

A

gram pos rods- branching

causes dental abcess, lung abcess, abdominal abcess, and sinusitis

some are aerotolerant

found in mouth and GI

sulfur granules seen in lesions

25
Q

anaerobic gram positive cocci

A

peptostreptococcus

peptococcus

26
Q

peptostreptococcus

A

anaerobic gram pos

normal flora of mouth, urogenitals, and GI tract

causes many infections- brain abscesses, pulmonary, obgyn

27
Q

peptococcus

A

gram pos anaerobes

oral, upper respiratory and gut flora
involved in oral, lung, and abdominal abscesses

28
Q

treatments of anaerobic infections

A

pencillin- except for bacteroides fragilis

clindamycin

newer cephalosporins

chloramphenicol

metronidazole

if mixed, use w/ aminoglycosides

surgical drainage of abscesses