Normal Antenatal Progress Flashcards

1
Q

What foods contain folic acid?

A

Dark green leafy vegetables
Oranges
Wholegrain
Yeast

(Bread, butter, cereal)

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2
Q

When does a woman need more than the recommended dose (400micrograms OD) of folic acid?

A

Anti-epileptic medication
Diabetes
Obesity
Chrohn’s/Coeliac

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3
Q

When are maternal antibodies produced?

A

When a mother is rhesus- and her foetus is rhesus+
Usually during delivery of 1st child
May destroy any subsequent rhesus+ foetuses

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4
Q

How do you prevent a mother with negative rhesus status from producing maternal antibodies?

A

Give Anti D antibodies

Routinely offered in the 3rd trimester to rhesus- mothers

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5
Q

Factor that make a woman high risk are?

A
Advanced maternal age >40 or low age <20
History of any medical problems 
Previous surgery
IVF treatment
Previous c-section
Previous problems in pregnancy - htn,growth restriction, diabetes, feral abnormalities
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6
Q

When do USS scans occur?

A

12 weeks - dating
20 weeks - growing well, no abnormalities (heart or NT defects)
26 weeks - glucose tolerance test

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7
Q

Levels of B-HCG in pregnancy

A

Peaks just before 3 months, and slowly drops from then until 9 months

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8
Q

Levels and function of oestrogen in pregnancy

A

Slowly rises throughout pregnancy until it rapidly drops at 9 months
Prepares the body for delivery throughout pregnancy, increasing the number of oxcytocin receptors in the uterus
Initially produced in the corpus luteum, and the later by the placenta

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9
Q

Levels and function of progesterone in pregnancy

A

Slowly rises throughout pregnancy until it rapidly drops at 9 months
Smooth muscle relaxant, maintains the uterine lining
Initially produced in the corpus luteum, and the later by the placenta

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10
Q

What is the combined test for Downs Syndrome?

A

PAPP-A
B-hCG
Nuchal Translucency

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11
Q

How do you diagnose gestational diabetes?

A

2 hour glucose >7.8

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12
Q

How does the respiratory system change during pregnancy?

A

Increase in intraabdominal pressure

  • diaphragmatic breathing
  • hyperventilation
  • increase in tidal volume
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13
Q

How does the cardiac system change during pregnancy?

A

Increase in cardiac output

Usually a drop in blood pressure (raise could mean pre eclampsia)

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14
Q

What haematological changes happen in pregnancy?

A

Increase in plasma volume (40%) - periph oedema
Increase in RBC volume (25%)
Leads to anaemia
Increase in clotting factors - hypercoagulability

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15
Q

MSK changes in preganacy

A
BMI increase
Stretch marks
Lower back pain
Lordosis
Sciatica
Muscle cramps
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16
Q

Endocrine changes in pregnancy

A

Increase in ant. Pituitary function
Human placental lactogen (gestational diabetes)
Increase in thyroid hormone

17
Q

Dermatological changes in pregnancy

A

Skin pigmentation
Distension and proliferation of blood vessels
Spider amigomata, facial flushing, striae gravidarium

18
Q

Gynaecological changes in pregnancy

A

Breast enlargement
Areolar pigmentation
Uterine hypertrophy
Cervical gland hypertrophy - causes increase of mucus secretion (thick mucus plug)
Vaginal lactobacilli proliferation, increases lactic acid and the pH of the vagina (protective)

19
Q

Breast changes in pregnancy

A

Increase in adipose tissue
Increase in lactiferous duct system
Enlargement of breast lobules (progesterone)

Progesterone = lobules
Oestrogen = ducts
20
Q

Changes in the urological system

A

Increased rental blood flow (40%)
Increased GFR
Increase kidney size
Ureter dilation (progesterone)

21
Q

Changes in the gastrointestinal system

A

Oesophageal sphincter relaxation (reflux)
Increase in intra-abdominal pressure (reflux, haemorrhoids)
Reduced bowel motility (constipation)

22
Q

What events in a previous pregnancy could impact of subsequent pregnancies?

A

Premature labour
Fetal growth restriction
Antepartum haemorrhage
Gestational htn/pre eclampsia/diabetes/thrombocytopenia
Type of delivery - c section, forceps, ventouse
3rd or 4th degree tear
Postpartum haemorrhage
Previous stillbirth, late miscarriage, neonatal death

23
Q

What bloods are taken at the booking appointment?

A
Hb 
Platelets
HIV, Syphillis, Hep B
Blood group and antibody status
Sickle cell and thalassaemia if high risk from family origin
24
Q

Risk factors for gestational diabetes

A
BMI >30
ethnicity - Black African, India 
FH - 1st degree relative with diabetes
PCOS
Previous baby >4.5kg @ delivery
Previous gestational diabetes

If any present = glucose tolerance test 26 weeks

25
Q

What is SFH?

A

Symphysis-fundal height (cm)

Plotted on a growth chart customised to maternal height, weight and ethnicity. Growth velocity can be monitored

26
Q

What is the approx maternal mortality rate in UK? (Death while pregnant or within 42 days)

A

Approx 11/100,000 (sepsis leading cause)

27
Q

Effects of disease on pregnancy - fetal risks

A

Fetal abnormality (diabetes, epilepsy, obesity)
Excessive growth (diabetes)
Poor growth - (hypertension)
Risk of still birth - (diabetes)

28
Q

Effects of disease on pregnancy - maternal risks

A

Pre-eclampsia (diabetes,HTN, renal disease, SLE)

Risk of gestational diabetes (obesity, steroid use)

29
Q

Effects of pregnancy on disease

A

Renal disease (can be long term)
Diabetes (increased insulin requirements)
Some cardiac problems

Some get better - RA, MS