NOREPINEPHRINE

Question 1

Norepinephrine

Amount Carried

Answer 1

Optional 4 mg

Question 2

Norepinephrine

Concentration

Answer 2

1 mg/ mL

Question 3

Norepinephrine

Indications

Answer 3

Severe hypotension due to cardiogenic, septic or neurogenic shock either refractory to intravascular fluids or in which fluid boluses are contraindicated

Question 4

Norepinephrine

Class

Answer 4

Natural catecholamine;

sympathomimetic

Question 5

Norepinephrine

Mechanism of Action

Answer 5

Primary alpha agonist

Question 6

Norepinephrine

Effects

Answer 6

vasoconstriction –> increase vascular resistance –> increase BP

Question 7

Norepinephrine

Dose/Route

Answer 7

IV drip at 2-4 mcg/min titrated to adequate BP.

Usual mix in D5W 4 mg/250 mL

Question 8

Norepinephrine

Side Effects

Answer 8

Hypertension –> stroke

Increased myocardial O2 demand –> ischemia/AMI

Question 9

Norepinephrine

Notes on Administration

Answer 9

Previously only used for interfacility transport. Added as an alternate option for Dopamine HCL (infusion pump required)