nontypical cell walls Flashcards
acid fast bacteria
mycobacterium and norcardia contain peptidoglycan and stain gram-positive, but bulk of cell wall is composed of unique lipids
acid fast bacteria
myocolic acid
very long chain fatty acid thick and waxy
found in cell walls of acid fast bacteria
contributes to the pathogenicity of the bacteria
makes bacteria highly resistant to certain chemicals and dyes
mycoplasmas and other cell wall deficient bacteria
mycoplasmas
naturally lack a cell wall
sterold in the cell membrane stabilize the cell against lysis
mycoplasma pneumoniae: walking pneumonia
nontypical cell walls
archaea
exhibit unusual and chemically distinc cell walls
some have cell walls composed entirely of polysaccharides
others have cell walls made of pure protein
all lack true peptidoglycan structure
some lack a cell wall entirely
cytoplasmic membrane structure
a lipid bilayer with proteins embedded
serves as a site for:
energy reactions
nutrient processing
regulates transport of nutrients and wastes
controls what goes in and out of cell
selectively permeable: special carrier mechanisms for passage of most molecules
prokaryotic plasma membrane
peripheral proteins
integral proteins
hopanoids
peripheral proteins
loosely associated with the membrane; easily removed
often play role in enzymatic reactions
integral proteins
embedded within the membrane; not easily removed
structural components for transport/secretion and respiration
hopanoids
embedded within the membrane
steroid like chains that provide a flexible but rigid framework for the membrane
outer membrane of gram negative bacteria contributes an extra
barrier
resistant to certain antimicrobial chemicals
more difficult to inhibit or kill than gram positive bacteria
alcohol based compounds dissolve lipids in the outer membrane and therefore damage the cell:
alcohol swabs used to cleanse the skin before certain medical procedures
treatment of infections caused by gram negative bacteria requires
drugs that can cross the outer membrane
the cytoplasm
70-80% of water
complex mixture of sugars, amino acids, and salts
plasmids
nonessential pieces of DNA
confer protective traits such as drug resistance and toxin and enzyme production
ribosomes
site of protein synthesis
composed of rRNA (60%) and protein (40%)
consist of large and small subunit