Nonmechanical pathology Flashcards

1
Q

if infection is suspected, what should you look for in radiological images of soft tissue?

A

soft tissue swelling, ulcers, subcutaneous air, skin thickening, cellulitis abscesses, fluid

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2
Q

if bone infection is suspected, what do you look for in images?

A

periosteal reaction, destruction

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3
Q

septic arthritis

A

infection involving a joint

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4
Q

bone infection

A

osteomyelitis

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5
Q

first line test for infection? 2nd line test (more sensitive)?

A

First line: X-ray (often negative); Second line; MRI or nuclear medicine bone scan

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6
Q

when looking for infection on MRI, what should you look for?

A

abnormal fluid collections and marrow edema

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7
Q

imaging signs of OA/DJD/Secondary arthritis

A
  1. loss of articular cartilage
  2. joint space narrowing
  3. osteophyte formation
  4. sclerosis
  5. subchondral cysts
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8
Q

most common jts for DJD/OA?

A

WB jts-hips, knees

Hands

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9
Q

Jts less frequently affected by DJD?

A

shoulder

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10
Q

RA: about

A

chronic autoimmune inflammatory disease; immune complex disease; characterized by joint swelling, joint pain and destruction; synovial inflammation

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11
Q

How is RA best diagnosed?

A

Classification criteria for RA; American College of Rheumatology (2010)

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12
Q

Categories of classification for RA

A

Joint involvement (# of jts involved, large vs. small jts); serology; acute phase reactants; duration of sx

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13
Q

Radiographic findings-RA

A

bilateral, proximal process; soft tissue swelling, osteoporosis, joint space narrowing, marginal erosions (away from WB portion of jt)

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14
Q

do you need an XR or MRI to diagnose RA?

A

NO: use classification scale; imaging shows response to tx, severity of jt damage

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15
Q

about gout

A

Gout caused by hyperuricemia resulting in deposition of monosodium urate crystals
Types: primary (inborn error of metabolism); secondary (disorders affecting urate metabolism-alcoholism); acute (mimics septic arthritis-jt swelling and pain); chronic (tophi erode bone)
Common sites: 1st MTP 90%; metatarsal, olecranon bursitis

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16
Q

Radiographic features of gout

A

Tophi: eccentric soft tissue swelling, usually not calcified; erosions with overhanging edges: reactive bone around a tophus, occur far from joint; joint space PRESERVED b/c deposition in articular cartilage is focal; narrowing only occurs late in the process

17
Q

Bisphosphonate-related atypical femoral fx: etiology

A

bisphosphonate: osteoporosis medication; reduces bone resorption resulting in increased bone mineral density; but also suppresses normal bone turnover resulting from normal activity; atypical fracture risk increased

18
Q

types of atypical fx related to bisphosphonate: radiologic signs

A

focal lateral cortical thickening: stress or fatigue fx involving cortex of bone
transverse fx
medial femoral spike: sharp medial cortical projection, typically arising from distal femoral segment
lack of comminution