Nonenzymatic Protein Function & Protein Analysis Flashcards
A repetitive organization of secondary structural elements is often referred to as ?
Motif
The structural protein with a trihelical fiber characteristic that makes up most of the ECM of connective tissue and is found throughout the body is known as ?
Collagen
-Essential for strength and flexibility
An essential component of the ECM of connective tissues that functions like a spring (coils and recoils) to restore the original shape of the tissue is known as ?
Elastin
Intermediate filament proteins found in epithelial cells that contribute to the mechanical integrity of the cell & also functions as regulatory proteins in termed ?
Keratins
-primary protein that makes up nails & hair
Movement of the ___ in a myosin subunit is responsible for ____ _____.
Neck; sarcomere contraction
Groups of glycoproteins that function to mediate Ca2+ dependent cell adhesions are ?
Cadherins
The weakest cell adhesion molecules that bind to carbohydrate molecule projections from other cells is termed ?
Selectins
What type of bonds hold antibodies together ?
Disulfide linkages and noncovalent interactions
The process of an antibody marking an antigen for destruction by a macrophage or other phagocytic cell is termed ?
Opsonization
Which channel is regulated by membrane potential change ?
Voltage gated channels
A large family of integral proteins that are involved in signal transduction is termed ?
G-protein coupled receptors
Adenylate cyclase increase, increase of camp level in cells:
Gs
inhibits adenylate cyclase, lower levels of camp in cell:
Gi
Activates phospholipase C, which cleaves P from cell membrane to form PIP2; PIP2 is then cleaved into DAG and IP3-which can open Ca2+ channels in ER
Gq
Migration velocity in electrophoresis is directly and inversely proportional to what?
Direct: electric field strength and net charge
Inverse: frictional coefficient
