Non specific immune response

Question 1

phagocytes made in

Answer 1

bone marrow from stem cells.

Question 2

types of phagocytes

Answer 2

neutrophils

macrophages

both engulf bacteria via phagocytosis.

Question 3

neutrophil

Answer 3

lobed nucleus granular cytoplasm.

circulate in blood can squeeze through pore in capillary walls

Question 4

macrophages

Answer 4

kidney shaped nucleus and clear cytoplasm.

accumulate in organs.

Question 5

phagocytosis stages

Answer 5

pathogen produce chemicals that attract phagocytes

phagocyte recognise non self proteins on the pathogen antigens and binds to it.

phagocyte engulfs pathogen and encloses it in a vacuole called phagosome.

phagosome combines with lysosome form phagolysosome.

enzymes in lysosome digest and destroy the pathogen.

Question 6

macrophages and engulfing.

Answer 6

they engulf pathogens digest um partially leave antigens intact.

antigens placed on outside of cell surface membrane.

antigen presenting cell

Question 7

phagocyte that has engulf releases

Answer 7

cytokines to signal to other phagocytes to move to site of infection.

Question 8

opsonins are

Answer 8

chemicals that bind to pathogens and tag them so they can be more easily recognised.

phagocytes have cell receptors that bind to common opsonins.