Non-SLL small lymphocytic (low-grade) lymphomas

Question 1

Variants of mantle cell lymphoma

Answer 1

MCL with small lymphocytic morphology
MCL with centrocytic morphology
MCL with blastoid morphology
MCL with plasmacytic morphology (very rare)

Non-nodal MCL (mantle cell leukemia)
GI-limited mantle cell lymphoma (classically polypoid)

Question 2

Two “pathways” of a CCND1/2/3-translocated Pre-B cell clone

Answer 2

Question 3

Leukemic MCL does not express. . .

Answer 3

SOX11

Question 4

Types of follicular lymphoma

Answer 4

Classic Follicular Lymphoma
Follicle Center Lymphoma (new)
Pediatric-type Follicular Lymphoma
Duodenal-type Follicular Lymphoma
Follicular Lymphoma of an Immune Privileged Site

Answer 5

Primary cutaneous follicle center lymphoma

Tumor of follicle centre cells, including centrocytes and variable numbers of centroblasts, with a follicular, follicular and diffuse, or diffuse growth pattern, that generally occurs in the skin of the head or trunk. 50% of all primary cutaneous B cell lymphomas, 10% of all primary cutaneous lymphomas.

Patients present with firm, erythematous to violaceous non-ulcerating plaques, nodules, or tumours of variable size.