non melanoma skin cancer

Question 1

what do you find keratinocytes

Answer 1

in the epidermis of the skin

Question 2

what do langerhan cells do

Answer 2

Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels. These cells determine the appropriate adaptive immune response (inflammation or tolerance) by interpreting the microenvironmental context in which they encounter foreign substances

Question 3

what do pickle cells do

Answer 3

Spinous cells, or prickle cells, are keratin producing epidermal cells owing their prickly appearance to their numerous intracellular connections. They make up the stratum spinosum (prickly layer) of the epidermis and provide a continuous net-like layer of protection for underlying tissue.

Question 4

2 most common types of non-melanoma skin cancer are

Answer 4

Basel cell carcinoma -75%
squamous cell carcinoma -20%

others make up 5%

Question 5

what are the risk factors for skin cancer

Answer 5

sun damage - UV radiation 
repeated sun burns 
Fitzpatrick skin type 1-2 - fair skin, blue eyes, blonde or ginger , hair albinism  
previous skin cancer 
elderly male 
actinic keratoses

Question 6

actinic keratoses lead to what type of cancer

Answer 6

Actinic keratoses are very common, and many people have them. They are caused by ultraviolet (UV) damage to the skin. Some actinic keratoses can turn into squamous cell skin cancer. Because of this, the lesions are often called precancer.

Question 7

BCC frequently occur on the upper back and can be slow growing flesh coloured nodules are destructive and removed via surgical excision

frequently occur on sun exposed sites - can be a sore that docent heal and form mets surgical excision

actinic keratosis

Answer 7

frequently occur together , common form of NMSC precancerous, can be small, scaly and patchy and developed into SCC - need topical therapies

Question 8

which cancer does not really form mets

Answer 8

BCC