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Hematology > Non-Malignant Neutrophilic Disorders > Flashcards

Non-Malignant Neutrophilic Disorders Flashcards

1
Q

Functional Disorder

A

Chronic Granulomatous Disease
Chediak Higashi

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2
Q

Cytoplasmic Abnormalities

A

May-Hegglin
Alder-Reilly

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3
Q

Nuclear Abnormalities

A

Pelger Huet

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4
Q

Chronic Granulomatous Disease

A

-sex linked males
-inability to degranulate oxidative bacterial products

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5
Q

Chediak Higashi

A

fusion of 1° and 2° granules so they’re unable to degranulate to kill bacteria

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6
Q

May-Hegglin

A

-cigar shaped Dohle like inclusions
-giant platelets, thrombocytopenia, and bleeding

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7
Q

Alder-Reilly

A

Large 1° granules in a single or multiple cell line
(differentiate from toxic granulation which is present in neutrophils alone)

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8
Q

Pelger Huet

A

dumbell/peanut shaped nucleus

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9
Q

Non-Malignant Neutrophilic Disorders

A

Chronic Granulomatous Disease
Chediak-Higashi
May-Hegglin
Aider-Peilly
Pelger-Huet

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Hematology (5 decks)

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