NMR And Chromatography

Question 1

Explain the uses of CDCl3, CCl4 and TMS in NMR

Answer 1

All inert

TMS is a reference molecule
It gives one peak
Upfield from others
It is easy to remove as it is volatile

Both solvents have no H atoms to give a signal in the spectra
CDCl4(P) is for polar molecules
CCl4(NP) is for non polar molecules

Question 2

In chromatography, substances moving further have a stronger affinity for …

Answer 2

the mobile phase - theyre more soluble

Question 3

How to view dots on TLC plate?

Answer 3

Using a UV lamp
OR
spray ninhydrin to show spots chemically