NMJ Disorders - Sachen Flashcards
1
Q
Tensilon test
A
Edrophonium injection in Myasthenia Gravis testing
2
Q
Treatments for MG
A
- AChE inhibitors
- Prednisone
- Immunosuppressives
- Plasma exchange / IVIg
- Thymectomy
3
Q
Drugs that can exacerbate or unmask MG
A
- Neuromuscular blockers
- Anticholinesterase inhibitors
- Steroids
- Thyroid supplements
- BOTOX
- Magnesium salts
- ***Aminoglycosides
4
Q
Lambert-Eaton…cause?
Common association?
A
Autoimmune attack of pre-synaptic voltage-gated Ca++ channels
Cancer
5
Q
Proximal weakness, loss of DTRs, myalgias, dry mouth. Better w/ exercise
Reflexes in MG?
A
Lambert-Eaton myasthenic syndrome
Normal in MG
6
Q
Treatment for Lambert-Eaton
A
Look for malignancy
AChE inhibitors
3,4-Diaminopyridine
Guanidine hydrochloride
- AE = marrow suppression
Immunosuppression
7
Q
Dry sore mouth and throat, blurry vision, diplopia, nausea, vomiting. Hypohydrosis, total external ophthalmoplegia, paralyses
A
Botulism
8
Q
Botulism - treatment
A
Monitoring w/ respiratory support and general medical care
Antitoxin (if possible)
