NMJ Flashcards
1
Q
Name a post synaptic NMJ disorder.
A
Myesthenia gravis: CMAP normal;
Decrement with 3Hz RNS, EMG: normal or early recruit
MUAPs- unstable or increased jitter or BSAPP
2
Q
Name pre synaptic NMJ disorders
A
Lambert Eaton and Botulism: CMAP decreased
Decrement 3Hz RNS, Increment 50Hz RNS (huge with LE)
EMG: LE normal or early; Botulism- fibs and psws
MUAPs- unstable/increased jitter or BSAPP
3
Q
What causes Myesthenia Gravis?
A
post synaptic- not enough ACH receptors to bind to
test proximal mms RNS ‘upper trap/spinal accessory nerve
4
Q
What causes Lambert Eaton syndrome?
A
pre synaptic- not enough ACH released- attacks voltage gated Ca channels
5
Q
What does fast RNS cause?
A
increased Ca influx which results in increased ACH getting released
