NCS instrumentation Flashcards
3 Variables
1.Intensity of stimulus voltage fixed (0-400N); Amperes (0-100)mA amount of current 2. Duration aka pulse width of stimulus (50-1000ms) 3. Rate of stimulus 1-50 stim/sec(Hz)
What do Pre Amp/Amplifiers do?
Convert low voltage signal to higher voltage copy
What does the Differential Amp do?
2 amps- measure diff b/w active and reference
Common Mode Signal
Seen in both amps (active and reference)
What is the Common Mode rejection ratio (CMRR)?
ability of amp to amplify desired signal while rejecting common mode signal; measured in decibals-clinical amplifiers >90Db
What does the HF/Low Pass filter do?
resistors filter out high frequency
What does the LF/High Pass filter do?
resistors filter out low frequency
What is recommended filter setting for motor studies?
LF- 2-10Hz; HF- 10KHz
What is recommended filter setting for sensory studies?
LF- 2-10Hz; HF- 2KHz
What is recommended filter setting for EMG?
LF- 20-30Hz; HF- 10KHz
What is effect if INCREASE LF filter?
DECREASE AMP and DECREASE LATENCY Stabilize baseline
What is effect if DECREASE LF filter?
INCREASE AMP and INCREASE LATENCY
What is effect if INCREASE HF filter?
INCREASE AMP and DECREASE LATENCY
What is effect if DECREASE HF filter?
DECREASE AMP and INCREASE LATENCY
What is typical sweep speed?
10ms/div = duration (entire screen) 100ms Set sweep speed at 100ms/div= duration of 1 second if have 10boxes across
What is CMAP?
summation of individual mm fiber action potentials
What is SNAP?
summation of individual sensory fiber action potentials
What do mixed studies test?
record largest sensory nerves (1a) afferent mm spindle, largest and most myelinated so usually affected 1st in demyelinating lesions
What does amplitude represent?
of fibers that depolarize
What does NCS duration represent?
measure of synchrony- extent that fibers depolarize at same time
What does conduction velocity measure?
speed of the fastest conducting fibers
How is motor conduction velocity measured?
calculated in proximal segment only! CV=distance/(prox lat-distal lat)
How is sensory conduction velocity measured?
calculated in proximal and distal segments distance/time
What temp should we maintain for NCS performed in UE and LEs?
UE-32 and LE >29
What is the effect of having decreased temp?
increased amp, duration, prolonged latency decreased CV
How does age variable affect CV?
decrease 1-2ms per decade past 20 years old
How does UE CV compare to LE CV?
UE CV is faster than LE CV
How does proximal CV compare to distal CV?
Faster proximal; closer to trunk/nutrition, larger diameter
How does segment size LONG vs SHORT studied affect calculations?
Measure a short segment, risk for more error, since small error has SIG effect on calculation
Describe a MUP morphology.
3 phases, amp-300-500uV, duration-<10-12ms
What does MUP EMG duration represent?
of mm fibers within motor unit. ‘pitch’ will increase as number of fibers and territory increases
What does a long duration MUP mean?
dull and thuddy, sign of chronic condition-motor unit remodeling
What does a Short duration MUAPs sound like?
‘crisp’
What does polyphasia represent?
measure of synchrony and axonal sprouting
What does MUP amplitude affect?
Volume
What does a unstable MUAP mean?
NMJ disorder or increased jitter
MM fiber recruitment follows what rule normally?
Rule of 5s 1 MU at 5Hz; 2nd MU will come in at 10Hz
How can you increase force?
Increase rate of fire (activation) or recruit more MUs
What is recruitment ratio?
Rate of fastest firing MU/total number of MUs >10= decreased recruitment (neuro); <5=increased/early recruit (myopathic)
What is decreased recruitment?
caused by LOSS OF MUAPs; conduction block or axonal loss, can’t bring enough soldiers to the fight
What is increased/early recruitment?
caused by LOSS OF MM FIBERS; get lots of MUs fire to produce small amount of force
Describe what chronic axonal loss MUs will look like.
large amp, long duration, polyphasic-reinnervated mms
What would demyelination look like on EMG?
MUAP morphology-normal-C.B-decreased recruit (GBS and CTS)
What would a myopathic MU look like?
decreased # of mm fibers- short duration low amp (BSAPP)
How many mm fibers can contribute to a MUP?
at max 12
How close to the needle tip do mm fibers have to be?
1-3mm
How many MUPs in each mm can be analyzed?
@ least 12; 4 quadrants-3 probes each quadrant
The mm fibers of 1 MU can be spread over oval x-sectional area of what size?
5mm
How many MUs can be recorded from needle tip?
12-15
A typical MU has how many phases?
3 phases
What would increase duration of MUP?
increased phases and turns; axonal sprouting/regeneration
Why would we have 0 MUPs?
No axons, complete CB, pain or lesion in CNS
What happens to mm fibers when needle is briskly moved in mm?
Depolarize the mm and get insertional activity
How long does normal insertional activity last?
<200-300ms
What is increased insertional activity?
>200ms; usually with myotonic disorders
What is decreased insertional activity?
mm damage/chronic denervation; if get resistance to needle insertion=poor prognosis since getting mm fibers turning into fibrotic tissue
To observe spon activity settings are…
10ms sweep speed, 50mV/div
What things can cause abnormal spon activity?
trauma, inflammation and denervation
Fibs and PSWs are signs of what?
acute ‘active’ denervation/mm membrane instability
Prejunctional
problem w/motor nerve terminal branch
Postjunctional
lesion in mm fiber
Any potential that fires <4-5Hz
is not under voluntary control
What types of potential do you see that are MFAP/post
fibs, psws, myotonic, CRD
What types of potential do you see that are MUAP/pre
fasiculation, myokymic, neuromytonia,cramps
What causes a EPP/EPS?
needle touches axon terminal causing depolarization
What is a unstable membrane potential cause by?
decrease in intracellular K+
What are EMG characteristics of fibs?
+deflection, 3phases, amp: 30-800uV, duration<5ms, regular fire rate (post-junct), click, raindrop
What are EMG characteristics of psws?
biphasic, duration 30-100ms
How soon post injury should EMG be performed?
3wks/21 days
What are EMG characteristics of EPS?
Irregular fire (pre), biphasic, -deflection, hiss/sputtering
Why is it incorrect to refer to fibs/psws as denervation potentials?
Can see them in myopathic conditions
What are EMG characteristics of Myotonic d/c?
+deflection, phases 2-3, duration 2-3ms, rate 50-100Hz, WAX AND WANE; dive bomber sound
What are EMG characteristics of CRDs?
Pacemaker ephatic D/C=chronic pathology, phases-polyphasic, duration 10-15ms, amp 50-1000uV, regular fire rate- MACHINE
What are EMG characteristics of myokymic d/c?
undulating/quivering skin, post radiation- same MUAP fires, burst, soldier marching
What are EMG characteristics of neuromyotonia d/c?
WANING, AMP decreasing, highest freq- stiffness ‘Issac’s Syndrome’
What is type of activity is in this picture?
CRDs
What is type of activity is in this picture?
End plate spike
What is type of activity is in this picture?
Fibrillations
What is type of activity is in this picture?
Myotonic discharge
What is type of activity is in this picture?
postive sharp waves
What is type of activity is in this picture?
Neuromyotonia
What is type of activity is in this picture?
Myokymic discharges
What is type of activity is in this picture?
MEPPs
Describe psudofacilitation regarding NCSs.
Amplitude increases but the area under waveform decreases. Not adding any new mm fibers to it; the mm fibers are just firing more synchronized.