NMBD Flashcards

1
Q

Sux TBW vs IBW

A

TBW

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2
Q

Sux standard intubation dose

A

1 mg/kg

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3
Q

Sux RSI dose

A

1.5 mg/kg

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4
Q

Sux duration

A

9-13 mins

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5
Q

Sux onset

A

30-90 seconds

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6
Q

Sux elimination half-time

A

47 seconds

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7
Q

Roc standard intubation dose

A

0.6-1 mg/kg

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8
Q

Roc RSI dose

A

1.2 mg/kg

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9
Q

Roc maintenance dose

A

0.1 mg/kg

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10
Q

Roc onset

A

45-90 seconds

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11
Q

Roc duration

A

30-60 mins

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12
Q

Roc TBW vs IBW

A

IBW

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13
Q

Vec TBW vs IBW

A

IBW

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14
Q

Vec intubation dose

A

0.1-0.2 mg/kg

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15
Q

Vec maintenance dose

A

0.02 mg/kg

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16
Q

Vec onset

A

2-4 mins

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17
Q

Vec duration

A

30-45 mins

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18
Q

Pancuronium TBW vs IBW

A

IBW

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19
Q

Pancuronium intubation dose

A

0.1-0.15 mg/kg

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20
Q

Pancuronium maintenance dose

A

0.02 mg/kg

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21
Q

Pancuronium onset

A

2-4 mins

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22
Q

Pancuronium duration

A

60-90 mins

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23
Q

Atracurium TBW vs IBW

A

IBW

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24
Q

Atracurium intubation dose

A

0.5-0.6 mg/kg

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25
Q

Atracurium maintenance dose

A

0.1 mg/kg

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26
Q

Atracurium onset

A

2-3 mins

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27
Q

Atracurium duration

A

30-60 mins

28
Q

Cisatracurium TBW vs IBW

A

IBW

29
Q

Cisatracurium intubation dose

A

0.1-0.2 mg/kg

30
Q

Cisatracurium maintenance dose

A

0.02 mg/kg

31
Q

Cisatracurium onset

A

2.5-3.5 mins

32
Q

Cisatracurium duration

A

45-60 mins

33
Q

Mivacurium TBW vs IBW

A

IBW

34
Q

Mivacurium intubation dose

A

0.15-0.25 mg/kg

35
Q

Mivacurium maintenance dose

A

0.1 mg/kg

36
Q

Mivacurium onset

A

2-3 mins

37
Q

Mivacurium duration

A

15-20 mins

38
Q

Which NMBD release histamine

A

mivacurium
atracurium
sux

39
Q

Which NMBD utilizes hofmann elimination

A

atracurium
cisatracurium

40
Q

What is the toxic metabolite produces by hofmann elimination

A

laudanosine

41
Q

Order in which volatile anes increase potency of NMBD

A

Des>Sevo>Iso>Halothane>N2O

42
Q

Which NMBD is NOT metabolized

A

Roc

43
Q

Which NMBDs have active metabolites (not related to hofmann elimination)

A

Vec
Pancuronium

44
Q

Which NMBD are at highest risk of anaphylaxis

A

Roc and sux

45
Q

Edrophonium MOA

A

electrostatic attachment

46
Q

Neostigmine MOA

A

formation of carbamyl esters

47
Q

Pyridostigmine MOA

A

formation of carbamyl esters

48
Q

Physostigmine MOA

A

formation of carbamyl esters

49
Q

Edrophonium dose

A

0.5-1 mg/kg

50
Q

Neostigmine dose

A

0.02-0.07 mg/kg

51
Q

Pyridostigmine dose

A

0.1-0.3 mg/kg

52
Q

Edrophonium onset

A

1-2 min

53
Q

Neostigmine onset

A

5-15 min

54
Q

Pyridostigmine onset

A

10-20 min

55
Q

Edrophonium duration

A

30-60 min

56
Q

Neostigmine duration

A

45-90 min

57
Q

Pyridostigmine duration

A

60-120 min

58
Q

Edrophonium metabolism

A

Renal 75
Liver 25

59
Q

Neostigmine metabolism

A

50/50 renal and liver

60
Q

Pyridostigmine metabolism

A

Renal 75
Liver 25

61
Q

Best pairing for neostigmine

A

glyco

62
Q

Best paring for pyridostigmine

A

glyco

63
Q

Best pairing for edrophonium

A

atropine

64
Q

Which anticholinergic affects HR the most

A

atropine

65
Q

Which anticholinergics cross the BBB (2)

A

scopolamine
atropine

66
Q

Which anticholinergic does not cross the BBB

A

glyco