NMB section and Reversal section Flashcards

1
Q

Sugammadex vial

A

100mg/ml

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2
Q

Sugammadex Dose

A

2 mg/kg (2 twitches), 4 mg/kg (no twitches), 16mg/kg (3 mins after induction)

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3
Q

Sugammadex Onset

A

Fast

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4
Q

Sugammadex Peak

A

Fast

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5
Q

Sugammadex Duration

A

Depends on dose

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6
Q

Sugammadex T1/2B

A

120 min

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7
Q

Sugammadex Elimination

A

Renal

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8
Q

Sugammadex MoA

A

y-cyclodextrin complexes with Rocuronium and Vecuronium

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9
Q

Glycopyrrolate (reversal adjunct) vial

A

0.2mg/ml

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10
Q

Glycopyrrolate (reversal adjunct) Dose

A

0.2 mg per mg of neostigmine

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11
Q

Glycopyrrolate (reversal adjunct) Onset

A

1 min

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12
Q

Glycopyrrolate (reversal adjunct) Peak

A

5 min

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13
Q

Glycopyrrolate (reversal adjunct) Duration

A

2-3 hours

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14
Q

Glycopyrrolate (reversal adjunct) T1/2B

A

80 min

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15
Q

Glycopyrrolate (reversal adjunct) Elimination

A

Hep/Renal

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16
Q

Glycopyrrolate (reversal adjunct) MoA

A

Anitmuscarinic

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17
Q

Neostigmine Vial

A

1mg/ml

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18
Q

Neostigmine Dose

A

0.02-0.07 mg/kg

max 5mg

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19
Q

Neostigmine Twitches dosing

A

2-3 twitches = 0.05 mg/kg, 4 twitches with fade= 0.04 mg/kg, 4 twitches with no fade = 0.015-0.025 mg/kg

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20
Q

Neostigmine Onset

A

1-5 min

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21
Q

Neostigmine Peak

A

5 min

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22
Q

Neostigmine Duration

A

60-120 min

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23
Q

Neostigmine T1/2B

A

60-120 min

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24
Q

Neostigmine Elmination

A

Hep/Plasma Cholinesterases

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25
Neostigmine MoA
Anticholinesterase
26
Cisatracurium Vial
2 mg/ml
27
Cisatracurium Intub
0.1-0.2 mg/kg
28
Cisatracurium Maint
0.02 mg/kg
29
Cisatracurium Onset
2-3 min
30
Cisatracurium Peak
3-5 min
31
Cisatracurium Duration
30 min
32
Cisatracurium T1/2B
30 min
33
Cisatracurium Elimination
Hofmann
34
Cisatracurium MoA
Nicotinic M Antagonist (Nn, presynaptic)
35
Vecuronium Vial
1 mg/ml
36
Vecuronium intub
0.1 mg/kg
37
Vecuronium Maint
0.05 mg/kg
38
Vecuronium Onset
2-3 min
39
Vecuronium Peak
3-5 min
40
Vecuronium Duration
30 min
41
Vecuronium T1/2B
1-1.25 hours
42
Vecuronium Elimination
Renal/Hep
43
Vecuronium MoA
Nicotinic M Antagonist (Nn presynaptic)
44
Rocuronium Vial
10mg/ml
45
Rocuronium Intub
0.6-1.2 mg/kg (RSI=1.2 mg/kg)
46
Rocuronium Maint
0.15 mg/kg
47
Rocuronium Onset
60-120 secs (1 min RSI)
48
Rocuronium Peak
1-3 min (1 min RSI)
49
Rocuronium Duration
30-85 min
50
Rocuronium T1/2B
1.4 hours
51
Rocuronium Elimination
Renal/Hep
52
Rocuronium MoA
Nicotinic M Antagonist (Nn presynaptic)
53
Succinylcholine vial
20 mg/ml
54
Succinylcholine Intub
1 - 1.5 mg/kg (1.5 mg/kg with all defasciculation dose of NMB
55
Succinylcholine Onset
30-60 sec
56
Succinylcholine Peak
60 sec
57
Succinylcholine Duration
4-6 min
58
Succinylcholine T1/2B
1 min
59
Succinylcholine Defasciculate
Defasciculate with 10% ED95, usually we give 0.03 - 0.06 mg/kg of Roc; 3-5 min before intubating dose
60
Succinylcholine MoA
ACh agonist
61
Succinylcholine Elimination
plasma cholinesterase