NMB section and Reversal section Flashcards
Sugammadex vial
100mg/ml
Sugammadex Dose
2 mg/kg (2 twitches), 4 mg/kg (no twitches), 16mg/kg (3 mins after induction)
Sugammadex Onset
Fast
Sugammadex Peak
Fast
Sugammadex Duration
Depends on dose
Sugammadex T1/2B
120 min
Sugammadex Elimination
Renal
Sugammadex MoA
y-cyclodextrin complexes with Rocuronium and Vecuronium
Glycopyrrolate (reversal adjunct) vial
0.2mg/ml
Glycopyrrolate (reversal adjunct) Dose
0.2 mg per mg of neostigmine
Glycopyrrolate (reversal adjunct) Onset
1 min
Glycopyrrolate (reversal adjunct) Peak
5 min
Glycopyrrolate (reversal adjunct) Duration
2-3 hours
Glycopyrrolate (reversal adjunct) T1/2B
80 min
Glycopyrrolate (reversal adjunct) Elimination
Hep/Renal
Glycopyrrolate (reversal adjunct) MoA
Anitmuscarinic
Neostigmine Vial
1mg/ml
Neostigmine Dose
0.02-0.07 mg/kg
max 5mg
Neostigmine Twitches dosing
2-3 twitches = 0.05 mg/kg, 4 twitches with fade= 0.04 mg/kg, 4 twitches with no fade = 0.015-0.025 mg/kg
Neostigmine Onset
1-5 min
Neostigmine Peak
5 min
Neostigmine Duration
60-120 min
Neostigmine T1/2B
60-120 min
Neostigmine Elmination
Hep/Plasma Cholinesterases