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Drug Sheet > Drugs > Flashcards

Drugs Flashcards

1
Q

Nitrous Oxide MAC

A

104

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2
Q

Nitrous Oxide Blood:Gas

A

0.47

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3
Q

Desflurane MAC

A

6

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4
Q

Desflurane MAC 60-70% N20

A

2.8

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5
Q

Desflurane Blood:Gas

A

0.42

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6
Q

Sevoflurane MAC

A

2.1

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7
Q

Sevoflurane MAC in 60-70% N20

A

0.66

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8
Q

Sevoflurane Blood:Gas

A

0.63-0.69

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9
Q

Isoflurane MAC

A

1.15

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10
Q

Isoflurane MAC in 60-70% N20

A

0.5

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11
Q

Isoflurane Blood:Gas

A

1.43

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12
Q

Lidocaine Onset

local anesthetic section

A

Rapid-Mod

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13
Q

Bupivicaine Onset

A

Moderate

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14
Q

Ropivicaine Onset

A

Moderate

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15
Q

Exparel (bupivicaine liposome injectable suspension) Onset

A

Moderate

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16
Q

Exparel Duration Spinal

bupivicaine liposome injectable suspension

A

96 hrs after local infiltration and 120 hours after interscalene brachial plexus nerve block

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17
Q

Exparel (bupivicaine liposome injectable suspension) MAX DOSE

A

266 Mg (20 ml)

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18
Q

Exparel (bupivicaine liposome injectable suspension) pKa

A

8.1

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19
Q

Exparel (bupivicaine liposome injectable suspension) Elimination

A

Hep

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20
Q

Exparel (bupivicaine liposome injectable suspension) Mechanism of Action

A

Amide NA+ channel Blocker

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21
Q

Ropivicaine Duration Spinal

A

2-3.5 hours

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22
Q

Ropivicaine Duration Epidural

A

120-180 mins

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23
Q

Ropivicaine MAX DOSE mg/kg

A

200mg plain/ 250 MG/epi

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24
Q

Ropivicaine Max dose plain mg/kg

A

3mg/kg

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25
Q

Ropivicaine Max Dose with Epi mg/kg

A

3 mg/kg

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26
Q

Ropivicaine pKa

A

8.1

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27
Q

Ropivicaine Elimination

A

Hep

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28
Q

Ropivicaine Mechanism

A

Amide Na+ BHannel Blocker

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29
Q

Bupivicaine Duration Spinal

A

2-3 hours

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30
Q

Bupivicaine Duration Epidural

A

120-200 mins

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31
Q

Bupivicaine Max Dose

A

175mg plain 225 mg/epi

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32
Q

Bupivicaine Max Dose Plain mg/kg

A

2.5 mg/kg

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33
Q

Bupivicaine pKa

A

8.1

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34
Q

Bupivicaine Elimination

A

Hep

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35
Q

Bupivicaine Mechanism of Action

A

Amide Na+ Channel Blocker

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36
Q

Lidocaine Duration Spinal

A

60-70 mins

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37
Q

Lidocaine Max Dose

A

350 mg plain, 500mg/epi

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38
Q

Lidocaine Max Dose Plain mg/kg

A

4.5 mg/kg

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39
Q

Lidocaine pKa

A

7.9

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40
Q

Lidocaine Elimination

A

Hep

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41
Q

Lidocaine Mechanism of Action

A

Amide Na+ Channel Blocker

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42
Q

Ondansetron vial

A

2mg/ml

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43
Q

Ondansetron Dose

A

4 mg

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44
Q

Ondansetron Conc

A

-

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45
Q

Ondansetron Onset

A

<30 min

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46
Q

Ondansetron Peak

A

2 hrs

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47
Q

Ondansetron Duration

A

12 hours

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48
Q

Ondansetron T1/2 Beta

A

3.5 hours

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49
Q

Ondansetron Elimination

A

Hep

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50
Q

Ondansetron MOA

A

5HT antagonist

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51
Q

Decadron vial

A

4 mg/ml

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52
Q

Decadron Dose

A

4mg/ml

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53
Q

Decadron Conc

A

-

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54
Q

Decadron Onset

A

5 mins / 4-8 hours

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55
Q

Decadron Peak

A

6-12 hours

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56
Q

Decadron Duration

A

24-72 hours

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57
Q

Decadron T1/2B

A

3.5 - 4.5 hours

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58
Q

Decadron Elimination

A

Hep

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59
Q

Decadron MoA

A

Glucocorticoid

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60
Q

Acetaminophen (Ofirmev) vial

A

1000mg /100ml

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61
Q

Acetaminophen (Ofirmev) Dose

A

1000 mg over 15 mins

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62
Q

Acetaminophen (Ofirmev) conc

A

10mg/ml

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63
Q

Acetaminophen (Ofirmev) Onset

A

15 mins

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64
Q

Acetaminophen (Ofirmev) Peak

A

1 hour

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65
Q

Acetaminophen (Ofirmev) Duration

A

4-6 hours

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66
Q

Acetaminophen (Ofirmev) T1/2B

A

2.4 hours

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67
Q

Acetaminophen (Ofirmev) Elimination

A

Hep

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68
Q

Acetaminophen (Ofirmev) MoA

A

Central inhibition of prostiglandin synthesis

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69
Q

Vasopressin Vial

A

20 units/ml

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70
Q

Vasopressin Dose

A

0.2 units

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71
Q

Vasopressin Conc

A

0.2 units/ml

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72
Q

Vasopressin Onset

A

< 1 min

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73
Q

Vasopressin Peak

A

15 mins

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74
Q

Vasopressin Duration

A

20 mins

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75
Q

Vasopressin T1/2B

A

10-20 min

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76
Q

Vasopressin Elimination

A

Hep

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77
Q

Vasopressin Mix

A

20 units in 100 ml

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78
Q

Vasopressin MoA

A

Vasopressin Receptors

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79
Q

Esmolol vial

A

10 mg/ml

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80
Q

Esmolol dose

A

1ml TTE/10 mg

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81
Q

Esmolol Conc

A

10mg/ml

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82
Q

Esmolol Onset

A

2 min

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83
Q

Esmolol Peak

A

10 min

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84
Q

Esmolol Duration

A

10-30 min

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85
Q

Esmolol T1/2B

A

8-9 min

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86
Q

Esmolol Elimination

A

nonspecific blood & Tissue Esterases

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87
Q

Esmolol Mix

A

n/a

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88
Q

Esmolol MoA

A

Beta 1 Antagonist

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89
Q

Labetalol Vial

A

5mg/ml

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90
Q

Labetalol dose

A

1 ml TTE/ 5 mg

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91
Q

Labetalol Conc

A

5 mg/ml

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92
Q

Labetalol Onset

A

2-5 mins

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93
Q

Labetalol Peak

A

5-15 mins

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94
Q

Labetalol Duration

A

2-4 hours

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95
Q

Labetalol T1/2B

A

5 hours

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96
Q

Labetalol Elimination

A

Hep/Renal

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97
Q

Labetalol Mix

A

n/a

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98
Q

Labetalol MoA

A

Beta 1&2 and Alpha Antagonist (7:1)

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99
Q

Glycopyrrolate vial

A

0.2 mg/ml

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100
Q

Glycopyrrolate dose

A

0.1 - 0.2 mg

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101
Q

Glycopyrrolate Conc

A

0.2 mg/ml

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102
Q

Glycopyrrolate Onset

A

1 min

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103
Q

Glycopyrrolate Peak

A

5 min

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104
Q

Glycopyrrolate Duration

A

2-3 hours

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105
Q

Glycopyrrolate T1/2B

A

80 mins

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106
Q

Glycopyrrolate Elimination

A

Help/Renal

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107
Q

Glycopyrrolate Mix

A

0.2mg/ml

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108
Q

Glycopyrrolate MoA

A

Antimuscarinic

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109
Q

Atropine Vial

A

0.4 mg/ml or 1 mg/ml

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110
Q

Atropine Dose

A

0.5 - 1 mg

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111
Q

Atropine Conc

A

1 mg/ 2.5 ml

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112
Q

Atropine Onset

A

1 min

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113
Q

Atropine Peak

A

2-4 min

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114
Q

Atropine Duration

A

30-60 min

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115
Q

Atropine T1/2B

A

4 hours

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116
Q

Atropine Elimination

A

Hep

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117
Q

Atropine Mix

A

0.4 mg/ml

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118
Q

Atropine MoA

A

Antimuscarinic

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119
Q

Epinephrine vial

A

1 mg/ml

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120
Q

Epinephrine dose

A

1 ml TTE/ 10 mcg

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121
Q

Epinephrine Conc

A

10 mcg/ml

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122
Q

Epinephrine Onset

A

30-60 sec

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123
Q

Epinephrine Peak

A

< 3 min

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124
Q

Epinephrine Duration

A

5-10 min

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125
Q

Epinephrine T1/2B

A

2-4 min

126
Q

Epinephrine Elimination

A

MAO/Hep

127
Q

Epinephrine Mix

A

0.1 ml of 1:1000 in 10 ml NS

128
Q

Epinephrine MoA

A

Direct Alpha & Beta Agonist

129
Q

Ephedrine vial

A

50mg/ml

130
Q

Ephedrine Dose

A

1 ML TTE/ 5 mg

131
Q

Ephedrine Conc

A

5 mg/ml

132
Q

Ephedrine Onset

A

< 1 min

133
Q

Ephedrine Peak

A

2-5 min

134
Q

Ephedrine Duration

A

10 min

135
Q

Ephedrine T1/2B

A

3 hours

136
Q

Ephedrine Elimination

A

Hep/Renal

137
Q

Ephedrine Mix

A

50 mg in 9 ML

138
Q

Ephedrine MoA

A

Direct and Indirect Alpha & Beta Agonist

139
Q

Phenylephrine vial

A

10mg/ml

140
Q

Phenylephrine Dose

A

1ml TTE/40 mcg

141
Q

Phenylephrine Conc

A

40 mcg/ml

142
Q

Phenylephrine Onset

A

< 1 min

143
Q

Phenylephrine Peak

A

1 min

144
Q

Phenylephrine Duration

A

5-10 min

145
Q

Phenylephrine T1/2B

A

2 hours

146
Q

Phenylephrine Elimination

A

Hep

147
Q

Phenylephrine Mix

A

10 mg in 249 ml

148
Q

Phenylephrine MoA

A

Alpha 1 agonist

149
Q

Sugammadex vial

A

100mg/ml

150
Q

Sugammadex Dose

A

2 mg/kg (2 twitches), 4 mg/kg (no twitches), 16mg/kg (3 mins after induction)

151
Q

Sugammadex Onset

A

Fast

152
Q

Sugammadex Peak

A

Fast

153
Q

Sugammadex Duration

A

Depends on dose

154
Q

Sugammadex T1/2B

A

120 min

155
Q

Sugammadex Elimination

A

Renal

156
Q

Sugammadex MoA

A

y-cyclodextrin complexes with Rocuronium and Vecuronium

157
Q

Glycopyrrolate (reversal adjunct) vial

A

0.2mg/ml

158
Q

Glycopyrrolate (reversal adjunct) Dose

A

0.2 mg per mg of neostigmine

159
Q

Glycopyrrolate (reversal adjunct) Onset

A

1 min

160
Q

Glycopyrrolate (reversal adjunct) Peak

A

5 min

161
Q

Glycopyrrolate (reversal adjunct) Duration

A

2-3 hours

162
Q

Glycopyrrolate (reversal adjunct) T1/2B

A

80 hours

163
Q

Glycopyrrolate (reversal adjunct) Elimination

A

Hep/Renal

164
Q

Glycopyrrolate (reversal adjunct) MoA

A

Anitmuscarinic

165
Q

Neostigmine Vial

A

1mg/ml

166
Q

Neostigmine Dose

A

0.02-0.07 mg/kg

167
Q

Neostigmine Twitches dosing

A

2-3 twitches = 0.05 mg/kg, 4 twitches with fade= 0.04 mg/kg, 4 twitches with no fade = 0.015-0.025 mg/kg

168
Q

Neostigmine Onset

A

1-5 min

169
Q

Neostigmine Peak

A

5 min

170
Q

Neostigmine Duration

A

60-120 min

171
Q

Neostigmine T1/2B

A

60-120 min

172
Q

Neostigmine Elmination

A

Hep/Plasma Cholinesterases

173
Q

Neostigmine MoA

A

Anticholinesterase

174
Q

Cisatracurium Vial

A

2 mg/ml

175
Q

Cisatracurium Intub

A

0.1-0.2 mg/kg

176
Q

Cisatracurium Maint

A

0.02 mg/kg

177
Q

Cisatracurium Onset

A

2-3 min

178
Q

Cisatracurium Peak

A

3-5 min

179
Q

Cisatracurium Duration

A

30 min

180
Q

Cisatracurium T1/2B

A

30 min

181
Q

Cisatracurium Elimination

A

Hofmann

182
Q

Cisatracurium MoA

A

Nicotinic M Antagonist (Nn, presynaptic)

183
Q

Vecuronium Vial

A

1 mg/ml

184
Q

Vecuronium intub

A

0.1 mg/kg

185
Q

Vecuronium Maint

A

0.05 mg/kg

186
Q

Vecuronium Onset

A

2-3 min

187
Q

Vecuronium Peak

A

3-5 min

188
Q

Vecuronium Duration

A

30 min

189
Q

Vecuronium T1/2B

A

1-1.25 hours

190
Q

Vecuronium Elimination

A

Renal/Hep

191
Q

Vecuronium MoA

A

Nicotinic M Antagonist (Nn presynaptic)

192
Q

Rocuronium Vial

A

10mg/ml

193
Q

Rocuronium Intub

A

0.6-1.2 mg/kg (RSI=1.2 mg/kg)

194
Q

Rocuronium Onset

A

60-120 secs (1 min RSI)

195
Q

Rocuronium Peak

A

1-3 min (1 min RSI)

196
Q

Rocuronium Duration

A

30-85 min

197
Q

Rocuronium T1/2B

A

1.4 hours

198
Q

Rocuronium Elimination

A

Renal/Hep

199
Q

Rocuronium MoA

A

Nicotinic M Antagonist (Nn presynaptic)

200
Q

Succinylcholine vial

A

20 mg/ml

201
Q

Succinylcholine Intub

A

1 - 1.5 mg/kg (1.5 mg/kg with all defasciculation dose of NMB

202
Q

Succinylcholine Onset

A

30-60 sec

203
Q

Succinylcholine Peak

A

60 sec

204
Q

Succinylcholine Duration

A

4-6 min

205
Q

Succinylcholine T1/2B

A

1 min

206
Q

Succinylcholine Defasciculate

A

Defasciculate with 10% ED95, usually we give 0.03 - 0.06 mg/kg of Roc; 3-5 min before intubating dose

207
Q

Succinylcholine MoA

A

ACh agonist

208
Q

Remifentanil vial

A

1 mg, 2mg, and 5 mg vials reconstitute powder in vial

209
Q

Remifentanil Load Dose

A

0.5 - 1 mcg/kg/min or 1 mcg/kg over 30-60 seconds

210
Q

Remifentanil Maint/hr

A

0.1-1.0 mcg/kg/min

211
Q

Remifentanil Onset

A

1-2 min

212
Q

Remifentanil Peak

A

3-6 min

213
Q

Remifentanil Duration

A

3-10 mins

214
Q

Remifentanil T1/2B

A

3- 10 mins

215
Q

Remifentanil Elimination

A

nonspecific blood & tissue esterase

216
Q

Remifentanil MoA

A

Mu opiod agonist

217
Q

Morphine sulfate Vial

A

10 mg/ml

218
Q

Morphine sulfate Load dose

A

2-10 mg/70 kg

219
Q

Morphine sulfate Maint/Hr

A

0.1 - 0.2 mg/kg

220
Q

Morphine sulfate Onset

A

5-14 min

221
Q

Morphine sulfate peak

A

19 min

222
Q

Morphine sulfate duration

A

2-4 hours

223
Q

Morphine sulfate T1/2B

A

2 hours

224
Q

Morphine sulfate Elimination

A

hep

225
Q

Morphine sulfate MoA

A

Mu Opiod antagonist

226
Q

Hydromorphone vial

A

1 mg/ml ; 2 mg/ml

227
Q

Hydromorphone Load dose

A

0.5-2 mg

228
Q

Hydromorphone Maint/Hr

A

n/a

229
Q

Hydromorphone Onset

A

10-15 min

230
Q

Hydromorphone Peak

A

10-20 min

231
Q

Hydromorphone Duration

A

2-3 hours

232
Q

Hydromorphone T1/2B

A

2-3 hours

233
Q

Hydromorphone MoA

A

Hep

234
Q

Hydromorphone Mix

A

dilute to 0.1 mg/ml

235
Q

Morphine sulfate Mix

A

dilute to 1 mg/ml

236
Q

Sufentanil vial

A

50 mcg/ml in 2 ml vial, dilute 100 mcg/8ml for 10 mcg/ml in 10 ml

237
Q

Sufentanil Load dose

A

1-2 mcg/kg (case 1-2 hours), > 8 mcg/kg primary anesthetic

238
Q

Sufentanil maint/hr

A

1 mcg/kg/hr of expected surgical time

239
Q

Sufentanil Onset

A

immediate (1-3min)

240
Q

Sufentanil Peak

A

2-3 min

241
Q

Sufentanil Duration

A

30-60 min

242
Q

Sufentanil T1/2B

A

2-3 hrs

243
Q

Sufentanil Elimination

A

Hep

244
Q

Sufentanil Mix

A

100mcg/8ml NS for 10 mcg/ml in 10 ml

245
Q

Sufentanil MoA

A

Mu opiod agonist

246
Q

Fentanyl Vial

A

50 mcg/ml

247
Q

Fentanyl Load Dose

A

2-20 mcg/kg

248
Q

Fentanyl Maint/Hr

A

1-2 mcg/kg

249
Q

Fentanyl Onset

A

1-3 min

250
Q

Fentanyl Peak

A

3-5 min

251
Q

Fentanyl Duration

A

30-60 min

252
Q

Fentanyl T1/2B

A

2-4 hours

253
Q

Fentanyl Elimination

A

Hep/Pulm

254
Q

Fentanyl MoA

A

Mu opiod agonist

255
Q

Lidocaine (induction) dose

A

1-1.5 mg/kg

256
Q

Lidocaine (induction) sedation

A

-

257
Q

Lidocaine (induction) Onset

A

45-90 secs

258
Q

Lidocaine (induction) Peak

A

1-2 min

259
Q

Lidocaine (induction) Duration

A

10-20 min

260
Q

Lidocaine (induction) T1/2B

A

1-2 hours

261
Q

Lidocaine (induction) Elminination

A

Hep

262
Q

Lidocaine (induction) MoA

A

Amide Na Channel Blocker

263
Q

Dexmedotomidine vial

A

100 mcg/ml

264
Q

Dexmedotomidine Dose

A

1 mcg/kg over 10 min

265
Q

Dexmedotomidine sedation

A

0.2-0.7 mcg/kg/hr

266
Q

Dexmedotomidine Onset

A

10-15 min

267
Q

Dexmedotomidine Peak

A

infusion

268
Q

Dexmedotomidine Duration

A

4 hours

269
Q

Dexmedotomidine T1/2B

A

2 hours

270
Q

Dexmedotomidine Elimination

A

Hep

271
Q

Dexmedotomidine MoA

A

Alpha 2 Agonist

272
Q

Midazolam vial

A

1 or 5 mg/ml

273
Q

Midazolam dose

A

0.15-0.35 mg/kg

274
Q

Midazolam Sedation

A

1-5 mg

275
Q

Midazolam Onset

A

30-120 secs

276
Q

Midazolam Peak

A

3-5 mins

277
Q

Midazolam Duration

A

15-80 min

278
Q

Midazolam T1/2B

A

1.5-3.5 hours

279
Q

Midazolam Elimination

A

Hep

280
Q

Midazolam MoA

A

BZ agonist on GABA

281
Q

Ketamine vial

A

50 mg/ml

282
Q

Ketamine dose

A

1-2 mg/kg

283
Q

Ketamine sedation

A

0.2-0.8 mg/kg

284
Q

Ketamine Onset

A

30-60 sec

285
Q

Ketamine Peak

A

60 secs

286
Q

Ketamine Duration

A

5-10 mins

287
Q

Ketamine T1/2B

A

3 hours

288
Q

Ketamine Elimination

A

Hep

289
Q

Ketamine MoA

A

NMDA Antagonist

290
Q

Etomidate vial

A

2mg/ml

291
Q

Etomidate dose

A

0.2-0.3 mg/kg

292
Q

Etomidate sedation

A

NO!!

293
Q

Etomidate Onset

A

30-60 sec

294
Q

Etomidate Peak

A

60 sec

295
Q

Etomidate duration

A

4-8 mins

296
Q

Etomidate T1/2B

A

3 hours

297
Q

Etomidate Elimination

A

Hep

298
Q

Etomidate MoA

A

GABA Agonist

299
Q

Propofol vial

A

10mg/ml

300
Q

Propofol dose

A

2-2.5 mg/kg

301
Q

Propofol Sedation

A

25-75 mcg/kg/min

302
Q

Propofol Onset

A

30-40 secs

303
Q

Propofol peak

A

60 secs

304
Q

Propofol duration

A

4-8 min

305
Q

Propofol T1/2B

A

1-3 hours

306
Q

Propofol Elimination

A

Hep/Pulm

307
Q

Propofol MoA

A

GABA agonist

308
Q

Bupivicaine Max dose Epi

A

3mg/kg

309
Q

Lidocaine Duration Spinal

A

60-120 mins

310
Q

lidocaine Max dose epi

A

7 mg/kg

311
Q

Rocuronium Maint

A

0.15 mg/kg

312
Q

Succinylcholine Elimination

A

plasma cholinesterase

Drug Sheet (10 decks)

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