Nitrogenous Compounds Flashcards
1
Q
Amine –> N-alkylated amine
A
Nucleophilic Substitution
Limiting R-X in ethanol, heat
2
Q
Amine –> Amide
A
Condensation
RCOCl, r.t.p.
3
Q
Amide –> COOH + NH3 / NH4+
Observation
A
Basic hydrolysis
NaOH, heat
Gas turns damp red litmus blue
4
Q
Amine –> NH3
Observation
A
Basic hydrolysis
NaOH, STRONG, prolonged heating
(usually will not happen)
Gas turns damp red litmus blue
5
Q
Proteins –> amino acids
A
Basic hydrolysis Conc HCl (6 mol dm-3), strong, prolonged heating
6
Q
NH3+/NH4+ –> NH3
A
Acid-base
NaOH, warm
7
Q
Amine –> NH3+ salt
A
Acid-base
HCl
8
Q
Nitrobenzene –> phenylamine
A
Reduction
Sn, conc HCl, heat, followed by NaOH
9
Q
Amide –> amine
A
Reduction
LiAlH4 in dry ether, r.t.p.
10
Q
Phenylamine –> 2,4,6-tribromophenylamine
A
Electrophilic Substitution
Br2(aq)
11
Q
Distinguish RCOCl and RCOOH
A
Add AgNO3
Observation: White ppt
Do not add Na2CO3
