Nitrogeneous Non Protein Flashcards

1
Q

Kreatin ditemukan pada

A

94% pada jaringan otot

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2
Q

Otot tidak mampu mensintesis kreatin, maka darimana asal kreatin itu

A

darah

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3
Q

Tempat biosintesis kreatin

A

ginjal

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4
Q

asam amino yang terlibat dalam biosintesis kreatin

A

arginin, metionin, glisin

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5
Q

secara in vitro, kreatin akan diuabh menjadi kreatinin per hari sebanyak

A

1,1%

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6
Q

3 komponen penyusun gluthathione adalah

A

glisin, asam glutamat, sistein

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7
Q

ikatan yang menghubungkan antara gugus amina sistein (yang melekat dengan ikatan peptida pada glisin) dengan gugus karboksil pada rantai samping glutamat adalah

A

ikatan gamma peptida

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8
Q

Glutation tereduksi disebut juga

A

GSH

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9
Q

Glutation sulfida teroksidasi disebut juga

A

GSSG

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10
Q

3 tempat penyimpanan glutation

A

hampir 90% di sitosol, 10% di mitokondria, sisanya di RE

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11
Q

GSH, GSSG, dan GS konjugat didegradasi dimana

A

empedu

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12
Q

enzim yang mendegradasi glutation

A

ectoenzymes katabolik gamma-glutamil transpeptidase
dipeptidase

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13
Q

elevasi bilirubin pada plasma

A

ikterus

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14
Q

anemia hemolitik, hepatitis virus, dan kanker pankreas disebabkan oleh

A

kegagalan ekskresi ikterus

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15
Q

penyakit yang disebabkan oleh mutasi gen yang mengkode biirubin UGT

A

Gilbert syndrome

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16
Q

mutasi pada gene encoding MRP-2 (multidrug resistance-associated protein 2) menyebabkan

A

hyperbilirubinemia