Genetics Flashcards

1
Q

Fungsi DNA Helicase

A
  • memutus ikatan hidrogen
  • unwind struktur double helix
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2
Q

Single Stranded DNA-binding Protein (SSB)

A

mencegah reannealing prematur pada DNA

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3
Q

DNA Topoisomerase

A

relieve torsional strain/memecahkan masalah supercoil atau untai DNA terlilit atau bengkok

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4
Q

jumlah ORI dari prokariota

A

satu

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5
Q

jumlah ORI eukariota

A

banyak (multiple)

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6
Q

enzim yang mengatasi masalah supercoils pada PROKARIOTA

A

DNA GYRASE

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7
Q

enzim yang mengatasi masalah supercoils pada EUKARIOTA

A

DNA TOPOISOMERASE

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8
Q

Sintesis DNA dimulai dengan menambahkan nukleotida dari bagian mana

A

gugus hidroksil 3’ di ujung primer

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9
Q

enzim untuk mensintesis RNA primer pada eukariota dan prokariota

A

DNA PRIMASE

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10
Q

enzyme for synthesizing or polymerizing DNA

A

DNA POLYMERASE

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11
Q

Enzim untuk removing RNA Primer

A

5’ to 3’ EXONUCLEASE

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12
Q

Stop Kodon

A

UAA, UAG, UGA

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13
Q

Start Kodon

A

AUG

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14
Q

Exonuclease Activity to carry out DNA Proofreading Mechanism

A

3’ to 5’

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15
Q

Exonuclease Activity to remove RNA primer

A

5’ to 3’

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16
Q

Enzim untuk terminasi pada proses replikasi DNA

A

DNA LIGASE

17
Q

OVERVIEW: 3 Enzim yang berperan pada inisiasi replikasi DNA

A
  1. HELICASE
  2. SSB Protein
  3. Topoisomerase (Eukariot) dan Gyrase (Prokariot)
18
Q

OVERVIEW: Enzim yang berperan pada elongasi replikasi DNA

A
  1. DNA PRIMASE
  2. DNA POLYMERASE
  3. EXONUCLEASE
19
Q

Enzim yang berperan pada DNA Repair

A

DNA POLYMERASE II (PROKARIOT)
DNA POLYMERASE BETA (EUKARIOT)

20
Q

3 tipe kerusakan pada DNA

A

Depurination,
Cytosine Deamination
Thyme Dimmers (pengaruh UV light)

21
Q

depurination adalah

A

melepas adenin dan guanin dari dna

22
Q

cytosine deamination

A

Cytosine berubah menjadi basa nitrogen lain

23
Q

thyme dimmers terjadi ketika

A

sinar uv menghubungkan dua basa nitrogen pirimidin yang berdekatan secara kovalen

24
Q

produk degradasi pirimidin

A

beta-alanin