NF2 Flashcards
1
Q
Extreme dual army tumors with NF2
A
schwannomas, meningioma
2
Q
neurofibromas
A
No neurofibroma in NF2
3
Q
Gen in NF2
A
22q 12.2> 📵 schwannomin tuomer suppressed peptide
4
Q
NF2 and intra-medullary tumors
A
More intrameduallry tumors in NF2
5
Q
By age of 30 in NF2
A
All patient affected by bilateral VS
6
Q
Diagnosis
A
7
Q
chance of preserving hearing in. Bilateral VS
A
If tumors small > attempts to remove it > if hearing preserved post op try to remove 2nd one
8
Q
F/u
A
Spinal mri to r/o Spain Al tumors
Annual mri brain until 4t decades
Hearing + BAER. Test and eye exam
9
Q
phenotypic subtypes of NF2
A
1.Wishart phenotype: severe. Early onset, myriad tumors and high tumor burden
- Gardner phenotype: mild. Later presentation, VS are the only tumors, slower deterioration of hearing
