New Flashcards
1
Q
What is the neurotransmitter that is responsible for neurotransmission in the nmj?
A
Acetylcholine
2
Q
Where is acetylcholine produced ??
A
In the cytoplasm
3
Q
How is acetylcholine produced??
A
By fusion of choline + Co enzyme A by the help of choline acetyl tranferase
4
Q
What are the 2 types of receptors do the Ach work on?
A
- Nicotinic (somatic) on muscles
- Muscarinic (sympathetic/glands & para on organs )
5
Q
How is the ion channel opened for muscarinic?
A
By binding Ach on 2 alpha subunits
6
Q
Maligmant hyperthermia is reversed by
A
Dantlorene
7
Q
What reverses BNZ
A
Flumazenil
8
Q
Lidocaine MOA
A
Na+ channel blockers
9
Q
Thiopental is used in ……. Surgeries and why?
A
Neurosurgery
1. Less ICP
2. Less cerebral blood flow
3. Decrease cerebral metabolic rate of o2
What other drug could be used???
Etomidate
10
Q
Thiopental is avoided in pts with….
A
Porphyria
11
Q
Etomidate side effect?
A
Myoclonus
