Neurulation Flashcards
1
Q
Neurulation
A
Neural plate rolls up to form the neural tube – driven by changes in cell shape
2
Q
Property of neuroepithelial cells
A
Neural plate neuroepithelial cells are polarised.
3
Q
What is on apical domain of neuroepithelial cells?
A
A band of F-actin is at the apical domain
4
Q
What happens when F-actin pulls tight? what interacts with it?
A
If this pulls tight, the cells are constricted at that edge and so change shape (imagine a purse string). - Many Molecules interact with F-actin to make it constrict.
5
Q
Folate
A
Changes in cell shape by folate which lead to changes in tissue shape.
As cellular apices constrict the tissue folds
Functions as a signal modifying cellular shape
