Introduction

Question 1

What is developmental neurobiology the study of?

Answer 1

how nervous system and it’ resident cell types form

Question 2

How is extrinsic information received?

Answer 2

one cell releases a signal that binds to a receptor on another cell and changes its fate

Question 3

How is intrinsic information inherited?

Answer 3

• daughter cell inherits fate specifying molecules present in mother cell
• asymmetric distribution of fate- determining molecules can make daughter cell with different identities

Question 4

what are many extrinsic and intrinsic instructions?

Answer 4

proteins encoded by genes

Question 5

what can differential gene activity explain?

Answer 5

restriction in potency

Question 6

what happens when a gene is expressed?

Answer 6

gene is transcribed and translated into a protein

Question 7

Function of enhancer?

Answer 7

activate transcription

Question 8

Function of silencer?

Answer 8

turn off transcription

Question 9

Function of transcription factors?

Answer 9

act as complex with other proteins

act on promotors/enhancers to activate or repress the transcription of specific genes

Question 10

What is differentiation? what is it governed by?

Answer 10

process by which cells become different from eachother and acquire specialized properties.
governed by changes i gene expression dictating proteins synthesised

Question 11

what is gene expression governed by?

Answer 11

extrinsic factors (morphogens) and intrinsic factors (transcription factors)