Neurotransmitters -- First Aid Flashcards
Norepinephrine (NE)
Diseased state = increased anxiety, decrease in depression
Synthesis = locus ceruleus (pons) – stress and panic
Dopamine (DA)
Diseased state = increased in Huntingtons, decreased in Parkinson’s, decreased in depression
Synthesis = ventral tegmentum and SNc (midbrain)
5-HT (serotonin)
Diseased state = increased in Parkinson’s, decreased in anxiety, decreased in depression
Synthesis = Raphe nucleus (pons, medulla, midbrain)
ACh
Diseased state = increased in Parkinson’s, decreased in AD, decreased in Huntington’s
Synthesis = Basal nucleus of Meynert
GABA
Diseased state = decreased in anxiety, decreased in Huntington disease
Synthesis = nucleus accumbens (reward center, pleasure, addiction, fear)