Neurotransmitters and synaptic transmission

Question 1

Synaptic transmission

Answer 1

1. AP arriving at terminal buttons trigger the release of NT into synapses where they bond to receptors on the membrane of the post synaptic neuron
2. NT bind to receptors which induce EPSP and IPSP
3. receptors are proteins selected for a specific NT
   exocytosis: the process of NT release
   Nt are synthesised in the cytoplasm and are packaged in vesicles

Question 2

Neurotransmitters

Answer 2

• there are over 100
• large molecule NT: neuropeptides, synthesised in cytoplasm by ribosomes
• small molecule NT: amino acids, synthesised in cytoplasm by Golgi complexes
• NT produce either excitation of inhibition
• Amino acids: building blocks of proteins

Question 3

Effects of drugs on NT

Answer 3

antagonists:drugs that inhibit effect of NT
agonists: drugs that facilitate effect of Nt (destroy enzymes)