Neurotransmitters and neurochemicals Flashcards

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1
Q

what are the parts of the neural pathway

A

pre-synaptic neuron (axon terminal), neural synapse, synaptic gap, post-synaptic neuron (recpetor site, dendrite)

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2
Q

what are the steps/process of the neural pathway

A
  1. The pre-synaptic neurons axon terminals release neurochemicals in the neural synapse 2. the neurotransmitters travel across the synaptic gap 3. the neurotransmitters bind to the specific receptors on the dendrites of the post-synaptic neuron
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3
Q

pre-synaptic neuron

A

the neuron that releases neurochemicals into the neural synapse

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4
Q

axon terminals

A

aka terminal buttons, they are the ends of a neuron that release neurochemicals into the neural synpase

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5
Q

synaptic gap

A

the space between the pre-synaptic neuron and post-synaptic neuron

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6
Q

post-synaptic neuron

A

the neuron that recieves neurocheimcals from the neural synappse

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7
Q

dendrites

A

branched extensions of a neuron where recpetor sites are located

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8
Q

recpetor sites

A

protein molecules on the dendrites of a neuron that recieve neurochemicals

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9
Q

neurochemicals

A

chemical substances that transmit neural information within the nervous system, how neuronsn communicate with one another

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10
Q

the steps/process of synaptic transmission

A
  1. neurochemicals are produced in the axon terminals of the pre-synaptic neuron 2. neurochemicals are releassed from the axon terminals of the presynatptic neuron into the synpatic gap 3. neurochemicals bind to specific nreceptor sites on the dendrites of the post-synaptic neuron 4. neurochemicals affect the post-synaptic neuron, either triggering or inhibiting a response
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11
Q

what are the two types of neurochemicals

A

neurotransmitters and neuromodulators

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12
Q

neurotransmitters

A

chemical molecules that have an effect on one or more post-synaptic neuron (localised effect), they enable rapid and short lived communication between two neurons across the neural synapse

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13
Q

what are the two categories neurotransmitters

A

exictatory and inhibitory

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14
Q

neuromodulators

A

chemical molecules that have an effect on multiple postsynapctic neurons (widespread modulatory effects as they can influence karge areas of brain tissue), they modulate neural activity more slowly but produce relatively long lasting effects

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15
Q

excitatory neurotransmitters

A

have an excitatory effect on the postsynaptic neuron, causing it to have a greater liklihood of firing an action potential

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16
Q

inhibitory neurotransmitters

A

have an inhibitory effect on the postsynaptic neuron, causing to have less liklihood of firing an action potential

17
Q

two specific neurotransmitters required to know

A

Glutamine and GABA

18
Q

Type and effect of glutamine

A

excitatory neurotransmitter (most abudant) and therefore increases the likelihood of the post-synaptic neuron firing an action potential

19
Q

type and effect of GABA

A

inhibitory neurotransmitter and therefore decreases the likelihood of the post-synatptic neuron firing an action potential

20
Q

glutamine role in functioning

A

importnat role in learning and memory , it strengthens synaptic connections between neurons that are repeatdely activated during learning, the strong synaptic connections represent memory of learning, enables synaptic plasticity, important role in thought and movement

21
Q

role in functioning of GABA

A

prevents overecitation of neurons, reduces anxiety by inhibiting extrectory neural signals that contribute to anxiety, important role in preventing seizures

22
Q

how to neuromodulators modulate the effects of neurotransmitters

A
  1. by changing the responsiveness of receptor sites of a particular neurotransmitter (enhacing excitatory/inhibitory effects) 2. changing the neurotransmitter release pattern of the pre-synaptic neuron
23
Q

what are the neuromodulators that we need to know

A

Dopamine and serotonin

24
Q

what is the effect of dopamine

A

dopamine can change excitatory and inhibitory effects on the postsynaptic neuron, the effect of dopamine depends on the type of recpetor sites present at the particular brain location

25
Q

what are the three roles in functioning of dopamine

A
  • coordinating voluntary motor movement
  • important role in reward based learning, behaviours that recieve a reward may cause the release of dopamine
  • also plays a role in motivation, given its role in reward based learning
26
Q

how does dopamine play a role in motivation

A

rewarding behaviours that trigger the release of dopamine have a pleasurable consequence for the person and are therefore more likely to be repeated (to experience the pleasure)

27
Q

what is a consequence of dopamine

A

it can be associated with addiction

28
Q

why is dopamine associated with addiction

A

addicting behaviours often provide an intensley pleasurable reward to the person, motivating them to repeat the behaviour, whnich consequently contributes to addiction

29
Q

serotonin effect

A

has inhibitory effects on the postsynaptic neuron

30
Q

three roles in functioning of serotonin

A
  • mood reglation and stablisation
    -regulating the sleep-wake cycle, including the quality and quantity of sleep and feelings or alertness and wakefulness during the day
    -apetite, digestion, arousal and nausea
31
Q

how do apropriate levels of sertonin in the brain affect mood

A

the person to experience stable and positive moods, promoting wellbeing.

32
Q

how to low levels of serotonin in the brain affect mood

A

low levels are associated with mental disorders including depression, correlation selationship, low levels doesnt cause depression

33
Q

how do medications relayte to neuromodulators

A

some medications used to treat depression increase serotonin levels or target serotonin receptors in the brain

34
Q

what is the sleep-wake cycle

A

the 24 hour period comprising time spent asleep and time spent awake

35
Q

differences in neuromodulates and neurotransmitters

A
  1. neuromodulators bind to multiple post synaptic synapsis whereas neurotransmitters bind to one or two post synaptic neurons 2. neuromodulators effects cause changes in multiple/widespread neurons whereas neurotransmitters directly effects change in the neuron it binds to 3. neuromodulators creates/modulates a slower and longer lasting response whereas a neurotransmitter creates a shorter/rapid response 4. neuromodulators modulate inhibitory or excitatory functions of neurotransmitters whereas neurotransmitters acts in excitatory or inhibitory role
36
Q

similarities between neurotransmitters and neuromodulators

A

both act as neurochemicals in the nervous system, both bind to speciifc receptor sites on the dendrites of the post synaptic neuron, both can lead to change in mental processes and behaviour