Neurotransmitter Exp of SZ Flashcards
What are neurotransmitters?
- Chemical messegers released by neurons allowing them to communitate with each other in the brain called synpatic transmission
What are the key roles of Dopamine?
- regulates mood
- attention
- movement
- learning (reward system)
- memory
What are the assumptions of dopamine in SZ?
SZ is caused by excess dopamine activity (hyperdopaminergia)
This is due to:
- smaller amounts of beta hydroxylaze eznymes breaking down dopamine leading to irregularity and build-up of excess dopmaine in the synapses
- large amounts of D2 receptors in the brain therfore more dopamine diffuses across the synapes
How does the symptoms of SZ related to the neurotrasmitter dopamine?
Causes of negative symptoms
- low activity of dopamine (hypodopamindergia) in the mesocortical pathway
Causes of positive symptoms
- high activity of dopamine (hyperdopaminergia) in the mesolimbic pathway
How does serotonin affect dopamine?
- Serotonin regulates dopamine
- if there is excess serotonin there will be excess dopamien
- if there’s irrgularity in serotonin it can cause negative symptoms