Neurosurgery Flashcards
Preop Considerations
Anticonvulsants - dose, frequency, last taken Continue DOS + supplementation NO sedation Antibiotics ordered/mixed Diuretics impact on electrolytes Stress dose steroids
Intraoperative Nerve Monitoring
Prevent brain, spinal cord, or nerve injury
MEP
SSEP
EMG
MEPs
Motor evoked potentials
Used in surgeries where motor track at risk
Direct & scalp electrodes
More sensitive to ischemia than SSEPs by 15min
Difficult to obtain d/t pre-existing or anesthetic conditions
NO paralytic
SSEPs
Somatosensory evoked potentials
Most commonly monitored
Stimulation peripheral sensory nerve
Mapping in spinal cord and sensory cortex
Ischemia detection in cortical tissue
Reduces risk of spinal cord/brainstem mechanical or ischemic insults
Paralytic okay sometimes
Motor monitoring less specific, does not measure motor deficits
EMGs
Electromyography
Reduces muscle electrical activity using needle pains
Continuous recording
Triggered responses
Used to detect nerve irritation, nerve mapping, assess nerve function, and monitor cranial nerves
Spinal surgeries to detect when screws are misplaced - passively monitors nerves
Stereotactic NSGY
Brain lab/mapping Fudicials affixed to patient scalp & forehead Interferes w/ Pox Smaller biopsies local or MAC Large resections require general
Craniotomy Medications
Induction - Fentanyl, Propofol, & Rocuronium Propofol 40-100mcg/kg/min Remifentanil 0.2mcg/kg/min Phenylephrine 0.2mcg/kg/min Decadron 10mg Mannitol 50-100g (0.25-0.5g/kg) Keppra 1g or Vimpat Vancomycin or Ancef Tylenol 30min prior wake-up Hydromorphone or Fentanyl Caffeine - adenosine receptor antagonist Physostigmine - anticholinesterase
Intracranial Mass Lesion
Clinical Presentation
Headache Seizures Focal neurological deficits Sensory loss Cognitive dysfunction
Supratentorial Mass Lesions
Seizures, hemiplegia, aphasia Frontal Parietal Temporal Occipital
Supratentorial Mass Lesion
Frontal
Personality changes, increased risk-taking, difficulty speaking (damage to Broca’s area)
Supratentorial Mass Lesion
Parietal
Sensory problems
Supratentorial Mass Lesion
Temporal
Problems w/ memory, speech, perception, & language skills
Supratentorial Mass Lesion
Occipital
Difficulty recognizing objects, an inability to identify colors, & trouble recognizing words
Infratentorial/Posterior Fossa Mass Lesions
Cerebellar dysfunction
Brainstem compression
Infratentorial/Posterior Fossa Mass Lesion
Cerebellar Dysfunction
Ataxia/poor balance, nystagmus, dysarthria, cannot perform rapid alternating movements, loss muscle coordination
Infratentorial/Posterior Fossa Mass Lesion
Brainstem Compression
Cranial nerve palsy, altered LOC, abnormal respiration
Primary Tumors
Glial cells - astrocytoma, oligodendroglioma, glioblastoma
Ependymal cells - ependymoma
Supporting tissues - meningioma, schwannoma, choroidal papilloma
Intracranial Mass Lesions
Anesthetic Considerations
Consider tumor location, growth rate, & size (slow growing tumors are often asymptomatic) EBL estimate
ICP elevation
Goals = control & maintain ICP
Anticipate sympathetic response w/ Mayfield head pins placement
Rapid emergence to allow neuro assessment
Intracranial Mass Lesions
Preop
Determine ICP
ICU patients w/ EVD
LOC & neuro deficits
Review PMH & general health status
Anticonvulsants & diuretics
Recent labs - glucose, drug levels, electrolytes, Hgb/Hct
Radiological studies - edema, midline shift, or ventricular size
Avoid benzodiazepines/narcotics
Continue corticosteroids & anticonvulsants
Intracranial Mass Lesions
Intraop
Hyperventilation maintain ETCO2 30mmHg Avoid excessive PEEP < 10 Glucose-free crystalloids or colloids Replace blood loss w/ blood or colloids EVD or lumbar drain to control ICP ↑CBF
Intracranial Mass Lesions
Monitors
A-line Foley IV access (central line?) PNS - do NOT monitor on hemiplegic side Ventriculostomy to monitor ICP (zero at auditory meatus) Consider IONM
Intracranial Mass Lesions
Positioning
Rotate HOB 90-180° Elevate 10-15° Supine, lateral, prone, or sitting Able to access all equipment IV tubing extension PNS on lower extremities
Intracranial Mass Lesions
Emergence
Slow & controlled
Prevent straining or bucking ↑ICP or worsen cerebral edema
Aggressive BP management systolic < 140-160
Hemorrhage or stroke risk - Clevidipine, Labetalol, and/or Esmolol
Neuro exam immediately after extubation
Do not administer any opioids until cleared by surgical team to prevent any neuro assessment impairment
Intracranial Mass Lesions
Postop
Admit to ICU for observation - seizures, neuro deficits, or ↑ICP
Transport w/ HOB elevated 30°
Manage HTN
Transport on O2
Minimal pain post-craniotomy (headache most common)
Awake vs. Asleep Craniotomy
Awake-awake
Asleep-awake
Asleep TIVA w/ IONM or GETA
Considerations for awake craniotomy patients:
Used for epilepsy surgery & tumor resection in frontal & temporal lobes where speech & motor need to be assessed intraop
Airway
Cooperation
Secure A-line & PIVs
Awake-Awake Craniotomy
No infusions until closing
Propofol bolus for pins
Hand-holding
Asleep-Awake Craniotomy
Start under GA w/ LMA or ETT
Wake patient up once tumor exposed
Propofol 40mcg/kg/min
Remifentanil 0.2-0.4mcg/kg/min