Neuropsychiatry Flashcards

1
Q

LGI1 encephalitis hallmarks

A
- Subacute history of cognitive 
 decline and seizures, refractory to 
 anticonvulsants 
- Faciobrachial dystonic seizures
- Unexplained hyponatraemia 
- Medial temporal lobe hyperintensities
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2
Q

NMDA encephalitis

A
Young, female, ?pcos
Prodrome - fever, headache, seizures
Cognitive decline, refractory AED seizure control 
Ovarian teratoma 
Mri - temporal lobe hyperintensities
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3
Q

Flags- limbic encephalitis

A
Atypical age at onset - FEP mid-30s
Acute-sub acute 
Cognitive decline 
Delirium
Seizure/motor symptoms - PD, myoclonic jerk, grimacing, writhing movements
Acute polymorphic course
Catatonia
Treatment resistant
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4
Q

Argyll Robertson pupil

A

Do not constrict to light

Do accommodate

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5
Q

Dorsolateral prefrontal cortex

A

Poor planning

Also impulse

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6
Q

Wilsons

A

ATP7B Cr 13 autosomal recessive
Copper
Personality changes, MCI, depression, 2% psychosis

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