Neuropsychiatry Flashcards
1
Q
LGI1 encephalitis hallmarks
A
- Subacute history of cognitive decline and seizures, refractory to anticonvulsants - Faciobrachial dystonic seizures - Unexplained hyponatraemia - Medial temporal lobe hyperintensities
2
Q
NMDA encephalitis
A
Young, female, ?pcos Prodrome - fever, headache, seizures Cognitive decline, refractory AED seizure control Ovarian teratoma Mri - temporal lobe hyperintensities
3
Q
Flags- limbic encephalitis
A
Atypical age at onset - FEP mid-30s Acute-sub acute Cognitive decline Delirium Seizure/motor symptoms - PD, myoclonic jerk, grimacing, writhing movements Acute polymorphic course Catatonia Treatment resistant
4
Q
Argyll Robertson pupil
A
Do not constrict to light
Do accommodate
5
Q
Dorsolateral prefrontal cortex
A
Poor planning
Also impulse
6
Q
Wilsons
A
ATP7B Cr 13 autosomal recessive
Copper
Personality changes, MCI, depression, 2% psychosis