Neurophysiology - trigeminal system Flashcards
What does the trigeminal system provide?
sensory innervation to the face and mucous membrane of the oral cavity
motor innervation to the muscles of mastication
What type of nerve is the trigeminal nerve?
branchiomeric nerve
What is a branchiomeric nerve?
innervates skeletal muscles of branchial arch
Where is the first synapse of the primary afferent neurons?
CNS
Describe the general sensory pathway of the trigeminal nerve?
What do you call a collection of cell bodies in the peripheral nervous system?
Ganglion
What are tracer methods? (anatomical)
HRP, fluorescent dyes, autoradiography
Applying dyes to see where the nerves are synapsing, where is the rain it ends up …
Apart from anatomical studied, how else can you study CNS structures?
Electrophysiological
How do you study the CNS electrophysiologically?
What type of peripheral stimuli excite cells in the nuclei
What part of the CNS is activated in response to stimuli
Intracellular recording
How do you study the CNS neuropathologically?
What happens if one or more nucleus is destroyed by disease (or surgery)
Where is the cell body of the trigeminal primary Afferent neurons?
Trigeminal ganglion
What do you call the second order neuron?
Trigemino -thalamic Tract
What are the 3 main parts of the brain stem?
What are the 3 main components of the trigeminal sensory neculei?
What are the primary Afferent of the main sensory nucleus?
Large diameter
Myelinated Afferent nerve fibers from V1,2,3
What do the primary afferents of the main sensory neuron synapse with? (2)
- Cross the midline, join the ventral trigeminothalmic tract and terminate in ventral posteromedial nucleus (VPM) of the thalamus
- Don’t cross the midline, joint the dorsal trigeminothalmic tract and terminate in VOM of the thalamus
What is the function of the main sensory nucleus?
Processing discriminative tactile
Processing proprioceptive sensation
Where do the spinal trigeminal nucleus extend to?
Both nucleus and tract extend caudally to about the third cervical segment of the spinal cord
What are the 3 parts of the spinal trigeminal nucleus?
What is the function of the spinal trigeminal nucleus?
Processing of pain and temperature information from the face, mouth and nose
What neurons cross the line between PNS and CNS?
Primary Afferent neurones
Where is the 2nd synapse of the general sensory pathway?
Thalamus
Where is the third general sensory synapse?
cerebral cortex
What happens between the 1st and 2nd synapse?
cross the midline
What are 3 different ways to study the CNS?
anatomical
Electrophysiological
Neurological/neuropathological
Where is the first synapse of the trigeminal sensory pathway?
trigeminal sensory nucleus
CNS