Neurophysiology: Neurons And ANS Flashcards
who developed the NIssl stain
German neurologist Franz Nissl
when was the nissl stain eveloped
late 19th century
what did the nissl stain show
The stain was a basic dye. it stained clumps of material surrounding the nuclei- called Nissl bodies
who developed the golgi stain
Camillo golgi
when was the golgi stain developed
1873
the golgi stain was developed from»>
silver reagents used in photography
what did the golgi stain show
Golgi stain shows neurons have at least 2 distinguishable parts: a central region that contains the cell nucleus and numerous thin tubes that radiate away from the central region called neurites
what did golgi propound from what he saw in his stain
He concluded that the neurites of different cells are fused together to form a continuous reticulum, or network, similar to the arteries and veins of the circulatory system.
whose research brought about the neuron doctrine
Santiago Ramon Y. Cajal
when was the neuron doctrine brought
1939
what was Cajal’s observation on the neuron
cajal said that the neurons were individual units (they existed as discrete entities). That is, neurons communicate by contact not continuity
when did golgi and cajal win the noble prize
1906
when was the neuron doctrine proved, and why?
The Neuron Doctrine was not proved until the development of in the 1950s. Neurons primarily communicate with one another at contacts called synapses (the exceptions being gap junctions).
the brains are composed of 2 cell types
-Neurons
-Glial cells
what are the glial cells
They outnumber the neurons 10:1. They insulate, support, and nourish injuries. They also remove degeneration debris
what are the glial cells of the CNS
-Astrocytes
-Oligodendrocytes
-Ependymal cells
-Microglia
what are the glial cells of the PNS
-Schwann cells
-satellite cells
what are the astrocytes
They are glial cells in the CNS that:
-maintain the blood-brain barrier
-provide structural support
-regulate ions
-regulate nutrients and dissolved gas concentrations
-They absorb and recycle neurotransmitter from scar tissue
what are the oligodendrocytes
They myelinate the axons of the CNS and provide structural framework
what are the ependymal cells
they line the ventricles of the brain and the central spinal canal. They participate in the production regulation and monitoring of CSF
what are the microglial cells
Remove cell debris, wastes and pathogens by phagocytosis
what are the satellite cells
they surround the cell bodies in the ganglia and regulate, the O2, CO2, nutrients and neurotransmitter levels around those neurons in the ganglia
what are the schwann cells
They surround all the axons in the PNS, myelinate them and take part in the process of repair after injury
Draw a neuron
check the book.