Neuropharmacology

Question 1

Which ion regulates the release of neurotransmitters from he nerve terminal?

Answer 1

Calcium

Question 2

Where are neurotransmitters synthesized?

Answer 2

Nerve terminal

Question 3

Where do neurotransmitters preside?

Answer 3

Nerve terminal

Question 4

By which specific mechanisms are neurotransmitters inactivated? (2)

Answer 4

Catabolism and reuptake

Question 5

In the nerve terminal, in what are neurotransmitters stored in?

Answer 5

Secretory vesicles

Question 6

What are hetero oligomers of amino acids? and give examples of these neurotransmitters (7)

Answer 6

Peptides.

• Opioid peptides
• B-endorphin
• Methionine enkaphalin
• Leucine enkaphalin
• Endomorphins
• Nociceptin
• Neurotrophins

Question 7

Chemically, what type of neurotransmitter is acetylcholine?

Answer 7

Ester (formed from an alcohol and an acid with the removal of water)

Question 8

Give 3 examples of neurotransmitters that are amino acids

Answer 8

-Glutamate, -GABA, -Glycine

Question 9

Give 4 example of neurotransmitters that are derivatives of amino acids

Answer 9

• Dopamine (DA)
• Noradrenaline (NA/NE)
• 5-Hydroxytryptamine
• Histamine

Question 10

Give an example of a nucleotide that is a neurotransmitter

Answer 10

Adenosine

Question 11

Give an example of a nucleoside that is a neurotransmitter

Answer 11

Adenosine triphosphate (ATP)

Question 12

Give two examples of gases that are neurotransmitters

Answer 12

• Carbon Monoxide

- Nitric Oxide

Question 13

What kind of neurotransmitter types are lipid derivatives?

Answer 13

Endocannabinioids

Question 14

What is the major excitatory NT in the CNS?

Answer 14

Glutamate

Question 15

What is the major inhibitory NT in the CNS?

Answer 15

ɣ-Aminobutyric acid (GABA)