Neuropathology Flashcards
1
Q
What is raised intracranial pressure?
A
mean CSF pressure over 200mm H20
caused by increased CSF volume, maybe due to intracranial space occupying lesion - neoplasm, haemorrhage, abscess, cerebral odema
2
Q
What is a consequence of increased intracranial pressure?
A
herniation
subfalcial
transtentorial
tonsillar - may cause compression of medulla with impairment of vital resp and cardiac functions
3
Q
give examples of space occupying lesions
A
extradural haemorrhage subdural subarachnoid intracerebral haemorrhage neoplasm abscess
4
Q
Describe ischaemic infarct histology
A
acute neuronal injury red neurons pyknosis of nucleus skrinkage of cell body Loss of nucleoli Intense eosinophilia of cytoplasm
