Neurons, Neurotransmission & the Nervous System Flashcards
What are neurons?
Nerve cells
The basic building blocks of the nervous system
What are the three main parts of a neuron?
Soma/cell body
Axon
Dendrites
What is the soma responsible for?
Keeping the cell alive
Contains the nucleus and therefore genetic material
What is the axon responsible for?
Conducts electrical impulses away from the soma to other neurons, muscles, or glands
What are the dendrites responsible for?
Collects messages from neighbouring neurons and sends them to the soma
What are the two things that neurons do?
Generate electricity that creates nerve impulses
Release chemicals to communicate with other neurons, muscles and glands
What are the three stages of electrical activity in neurons?
Resting potential
Action potential
Return to resting potential
Describe resting potential
Substances are able to pass through the cell membrane of the neuron via ion channels
The ions that remain within the axon of the neuron are more negatively charged than those that pass to the outside of the cell
This results in a net negative charge (polarisation)
Describe action potential
The electrical shift that occurs when a neuron is stimulated
Positive sodium ions enter the neuron
This causes a brief depolarisation, which begins at one end of the axon and moves down along it
Describe what happens after an action potential
There is a recovery period (the absolute refractory period) where the membrane is not excitable and cannot discharge another impulse
What are the two benefits of the absolute refractory period?
It stops the charge from moving backwards along the axon
It limits how often a neuron can fire
What is an “all or none event” ?
The idea that action potentials occur either at a uniform and maximum intensity, or not at all
What is a graded potential?
A change in the negative resting potential that does not reach the action potential threshold
What is special about graded potentials?
Multiple graded potentials may combine to trigger an action potential in certain circumstances
What is the myelin sheath?
A layer of fatty insulation that surrounds the axon
It allows electrical conduction to take place at a higher speed (due to the nodes of Ranvier)
Give an effect of damage to myelin sheath
Multiple sclerosis
How do neurons communicate with each other?
Via synapses
What is a synapse?
The conjunction of the axon terminal of one neuron and the membrane of another neuron
What is the synaptic space?
The tiny gap between the axon terminal of one neuron and the next neuron
What is a pre-synaptic neuron?
A neuron that sends messages