Neuronal identity Flashcards
1
Q
What happens after lateral inhibition?
A
Neuroblast
Neuroblast then divides to form neurons.
Ganglion mother cell and secondary neuroblast forms neuron-neuron, neuron-glia, glia-glia
2
Q
How are neuroblasts divided?
A
Asymmetric distribution of certain proteins in neuroblast
3
Q
What causes neuronal diversity?
A
Generated by chemical gradients
Roof plate - Neural crest cells, sensory neurons, BMP
Floor plate - V1, V2 interneurons, motoneurons, sonic hedgehog
4
Q
What do Hox genes do?
A
Hox genes pattern the neural tube (brain and spinal chord)
Anterior-posterior identity is induced by the protein products of Hox genes.
