Electrophysiology and neuronal signalling I Flashcards
1
Q
Depolarisation and hyperpolarisation
A
Depol - Membrane potential more +
Hyper - Membrane potential more -
2
Q
What is net movement directed by?
A
Electrical potential and chemical potential
3
Q
Patch clamp recording advantages and disadvantages
A
ADV
Can record single channels without changing the properties
DIS
Can’t change external medium in channel and RP unknown
4
Q
Excised patches ADV and DIS
A
ADV Can record single channels Can change inside and outside solutions DIS May change channel properties
5
Q
Whole cell ADV and DIS
A
ADV Control of MP and current Multiple channel recording but only single channel properties recorded DIS Higher noise and leakage current
