Neuromuscular Relaxants

Question 1

What do neuro.mu relaxants do?

Answer 1

selectively block the nicky R at the NMJ

Question 2

How can a degree of mu relaxation be achieved?

Answer 2

by blockade of interneurons at the level of the spinal cord

Question 3

(Which one is less selective? What is it limited to?)

Answer 3

blockade of interneurons at the level of the SC. (limited to tx of mu spasms due to injury, upper motor neuron dysfunction or certain ortho)

Question 4

(What are the five main uses?)

Answer 4

1. tx of spastic muscle conditions
2. relaxation of larynx for endotracheal intubation
3. to prevent muscular contraction during ECST
4. relaxation of chest during mechanical ventilation
5. adjuvant to anesthesia during surgery