Neuromuscular Junction Flashcards
Which branch of the nervous system controls contraction of skeletal muscles?
Somatic Motor
What structures is part of the presynaptic neuron of a neuromuscular junction?
Axon Terminal and Calcium voltage-gated channels
What is the neuromuscular junction? (NMJ)
Chemical synapse between an efferent neuron of the somatic motor division and skeletal muscle cell; allows the electrical signal of the neuron to be translated to neurotransmitters that will excite the skeletal muscle cell resulting in contraction
What receptors does the NMJ contain?
High density of chemically-gated ion channels or Ach receptors
What sarcolemma region is associated with the NMJ?
the motor endplate
Where will efferent neurons of the somatic motor system travel?
in spinal nerves and synapse with skeletal muscle cells at the neuromuscular junctions
What regions are in the Neuromuscular Junction?
A. Somatic motor neuron
B. Axon Terminal
C. Synaptic cleft
4. Skeletal muscle cell
What happens at the motor end plate?
At this region, the sarcolemma is folded to create an increase in surface area –> allows for a high concentration of protein cation chemical-gated channels called acetylcholine receptors
What happens after Ach receptors come into situation?
Acetylcholine receptors bind to acetylcholine to open –> there is a flow of sodium ions into of the cell and potassium ions out of the cell. The net difference is positive and is called end plate potential
True or False: The summation of many end-plate potential will result in an action potential in the skeletal muscle cell
True