Neuromuscular Disorders (Lecture) Flashcards
What are the primary sites of pathology for ALS, MD, GBS, PPS, and MS?
GBS: Peripheral nervous system demyelination
ALS and PPS: Anterior horn cell and motor neuron
MS: CNS demyelination
MD: muscle
What are the 4 basic clinical syndromes?
Generalized Peripheral Neuropathy: Longest peripheral nerve fibers involved.
Focal Peripheral Neuropathy: Localized disorders of single nerves anywhere from spinal root to smallest branch of the nerve.
Mononeuropathy Multiplex: individual peripheral nerves or their branches are involved at several sites giving rise to multi-focal signs and symptoms.
Mononeuropathy Multiplex and Polyneuropathy may co-exist: often motor and sensory S&S exist.
What are the S&S, cause, stages, and treatment (general) of GBS?
slides 11-13
what are the PT assessment guodelines for GBS wrt impairments, activity limitations, and participation restriction?
- slides 14-17
descrbe PT intevention in the acute phase of GBS
slide 18-20
descrbe PT intevention in the plateau phase of GBS
slide 21
descrbe PT intevention in the recovery phase of GBS
slide 22-23
describe the overall Pt summary for GBS patients
Intervention goals:
- Resolve respiratory problems
- Minimize pain
- Prevent secondary effects of immobilization
- Promote recovery of muscle strength and function
For peripheral neuropathy: Inadequate evidence to evaluate the effect of exercise on functional ability but some evidence points to the benefit of strengthening exercises.
what is post-polio syndrome?
progressive clinical syndrome consisting of new weakness, fatigue and pain in those individuals who have recovered from past paralytic polio
- poliomyelitis (polio), a contagious viral illness that in its most severe form causes paralysis, difficulty breathing and sometimes death
- infection leads to inflammation of nerve cells in the ventral horns of the spinal cord – damages motor neurons (anterior horn cells)
how do you make a post-polio diagnosis?
- slide 28
what is the etiology of post polio syndrome?
- slide 29
hwta happens to motor units after a polio onset?
slide 30-32
what are risk factors of post-polio syndrome?
slide 33
what things need to be managed with post-polio syndrome patients?
identification and treatment of other medical and neurological disorders which can mimic the symptoms of PPS
weakness
fatigue
pain
other problems (pulmonary dysfunction, dysphagia, and psychosocial difficulties
how to manage weakness for post-polio syndrome patients - and treatment guidelines
slide 35-39
what are the key muscle groups to assess for post polio syndrome?
how to assess, manage, and treat fatigue for post-polio syndrome patients
slide 40-44
describe the management/treatment of pain symptom for post-polio patients
slide 45-48
what is the prognosis for people with post-polio syndrome?
slide 50
what is MS? what causes it and how does it progress?
slides 51 and 52
what are the outcome predictors for MS?
slide 53
how do you reach an ms diagnosis?
slide 54
what is the medical management of ms?
slides 55-57
what are the most common symptoms of ms?
slide 58
evidence-infomred practice for MS
slide 60
what are the goals of rehab for Ms patients?
slide 61
for Ms, describe how the type of PT intervention depends on the stage od the disease
slide 62
explain good and bad responses to therapy for MS patients
what assessment scales are most commonly used for MS?
slide 64-68
describe management of fatigue for patients with MS. primary vs secondary fatigue
slides 69 - 72
describe management of muscle weakness for patients with MS - and exercise perscription
slides 73-74
describe PT management of spasticity for MS patients
slide 75
describe functional mobility management for MS patients
slides 76 - 78
describe PT management for MS patients for lack of balance and coordination
slide 79
describe PT management of deconditioning for MS patients
slides 80 and 81
describe PT management of sensory dysfunction for MS patients
slide 82
describe PT management of psychosocial issues for MS patients
- Employment
- Family coping
- Social life
overall: AN EFFECTIVE INTERVENTION CAN HELP GAIN OR SUSTAIN FUNCTION AND MAINTAIN ACTIVITY LEVEL
what is ALS? what structures does it involve?
slides 87-88
how to reach a clinical diagnosis of ALS
slide 89
onset and symptoms of ALS?
slide 90
ALS treatment and immediate care after diagnosis
slide 91, 92
PT goals for patient with ALS
slide 94
describe typical PT assessment for ALS patients - also measures used to track evolution of symptoms
slides 95-97, 105
describe the phases and stages of ALS (general)
slide 98
describe exercise and rehab guidelines for ALS patients in phase 1
slides 99-101
describe exercise and rehab guidelines for ALS patients in phase 2
slides 102-103
describe exercise and rehab guidelines for ALS patients in phase 3
slide 104, 106
in summary, what are the parameters for a submaximal strengthening exercise program for persons with a neuromuscular disease such as Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Post-Polio Syndrome or Guillain-Barre Syndrome?
slides 104-110
describe upper vs lower motor neuron symptoms
