Neurology of Systemic Disease

Question 1

In which of the following areas is ischemic cerebral damage after cardiac arrest most notable?

Answer 1

CA1 pyramidal neurons in the hippocampus

Question 2

According to current clinical practice guidelines, prognostication after cardiac arrest should be delayed for at least how long after initial injury?

Answer 2

72 hours

Question 3

Quais áreas do SNC são mais afetadas após uma isquemia cerebral secundária a PCR, por ex.? (áreas de alto metabolismo)

Answer 3

CA1 pyramidal neurons in the hippocampus (leading to memory impairment), cerebellar Purkinje cells (leading to ataxia), thalamic reticular neurons (leading to impaired arousal and attention), striatal neurons (leading to postanoxicmyoclonus), and pyramidal neurons in layers 3, 5,
and 6 of the neocortex (leading to impairment in attention, processing speed, and executive function)