Neurology chapter 11 carpal tunnel syndrome Flashcards

1
Q

Carpal Tunnel Syndrome

Description

A
  • Entrapment neuropathy of the median nerve at the wrist that causes mechanical compression, local ischemia and damage to the median nerve.
  • also known as “wake and shake syndrome”
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2
Q

CTS

Etiology

A
  • median nerve is entrapped or compressed as it passes through a tunnel composed of the carpal bones and the transverse carpal ligament.
  • any condition that results in edema may precipitate CTS.
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3
Q

CTS

incidence

A
  • affects 1.3 per 1,000 patients
  • women > men 3-10:1
  • predominant age is 40-60 years
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4
Q

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Risk factors

A
  • repetitive flexion, pronation, and supination of the wrist.
  • tenosynovitis of the flexor tendons of the fingers.
  • local trauma
  • prolonged improper positioning
  • weight gain, obesity
  • pregnancy or premenstrual edema
  • arthritis
  • hyperthyroidism
  • diabetes
  • metabolic conditions
  • space-occupying lesions
  • fractures
  • tumors
  • inflammatory diseases
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5
Q

CTS

Assessment findings

A
  • median paresthesias affecting the thumb, index finger, middle finger, and radial side of the ring finger.
  • nocturnal paresthesias.
  • bilateral presentation common at first, but may be unilateral.
  • Positive Phalen’s, and Tinel’s test
  • dull, aching sensation in hand, wrist, forearm, or upper arm.
    weakness and sensory loss; dropping objects from affected hand
  • affected hand may be cool to touch, pale in color, with dry skin.
  • atrophy of thenar muscle
    Blood pressure cuff inflated on the arm may precipitate symptoms.
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6
Q

Phalen’s test

A
  • hold flexed fingers against each other with wrists flexed at a 90 degree angle for 60 seconds.
  • considered positive if paresthesia occurs.
  • high specificity, low sensitivity
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7
Q

Tinel’s test

A
  • percuss over the median nerve on the volar aspect of the wrist.
  • considered positive if paresthesia occurs.
  • high specificity, low sensitivity.
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8
Q

CTS

Differential diagnosis

A
  • De Quervain’s syndrome
  • cervical radiculopathy
  • lesion of the brachial plexus
  • peripheral neuropathy
  • thoracic outlet syndrome
  • multiple sclerosis
  • CVA
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9
Q

CTS

Diagnostic studies

A
  • nerve conduction studies of the median nerve: delayed latency across the wrist confirms the diagnosis.
  • consider EMG, especially if nerve conduction studies are negative.
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10
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Prevention

A
  • frequent rest periods when repetitive wrist motions are performed
  • proper hand/wrist positioning
  • avoidance of risk factors
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11
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CTS

Nonpharmacologic management

A
  • correct underlying disorder
  • avoid aggravating factors
  • limit full extension and flexion of the wrist
  • reduce heavy work activities
  • avoid repetitive movements
  • splinting of wrists in neutral position with fingers free: wear for 4-12 weeks, mostly at night, may wear in day for activities that may aggravate the condition, consider adding steroid treatment if no relief after 1 month.
  • surgical decompression of the carpal tunnel with release of the transverse carpal ligament and debridement.
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12
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Pharmacologic management

A
  • NSAID’s in doses sufficient for anti-inflammatory effect.
  • combined nonsurgical and pharmacologic interventions may be most effective.
  • Intermediate-acting corticosteroid injection. Maximum three injections in 2 to 3 month intervals: inject with or without local anesthetic.
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13
Q

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Pregnancy / lactation considerations

A
  • pregnancy is a risk factor due to edema.

- local injection of anesthetic and hydrocortisone useful during pregnancy.

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14
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CTS

Consultation / Referral

A
  • surgeon if severe or persistent despite conservative therapy.
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15
Q

CTS follow-up

A
  • evaluate effect of conservative therapy (splints, NSAIDs, and cortisone injections)
  • postoperative evaluation by surgeon
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16
Q

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Expected Course

A
  • if untreated, risk of permanent loss of function in affected hand.
  • recurrence likely with nonsurgical interventions.
  • recurrence is unusual following surgery.
17
Q

CTS

Possible complications

A
  • pain after steroid injection
  • steroid injection may increase blood sugar, especially in patients with diabetes
  • postoperative infection
  • surgical complications
  • permanent damage from prolonged median nerve compression (thenar atrophy)