Neurology Flashcards
Afib stroke prophylaxis?
coumadin
Stroke on aspirin, tx?
Aspirin + dipyridamole
Focal neurologic deficit, no bleed, within 3 hours of presentation, tx?
tPA
Stroke secondary prophylaxis (what do you put them on after first stroke)?
Aspirin
Hemorrhagic stroke BP goal?
MAP < 110
Stroke, no tPA given - BP goal is?
220/120
New onset focal neurologic deficit, next step?
non-con CT
Ultrasound greater than 70% stenosis?
endarterectomy
On the test, when do you use clopidogrel?
aspirin intolerance
What drug is used to minimize vasoconstriction and delayed brain ischemia that can occur after subarachnoid hemorrhage?
nimodipine (CCB)
___ is an abnormal hypersynchronous electrical discharge of neurons.
Seizure
Among partial seizures, those in which __ is impaired are termed __, whereas those in which __ is preserved are termed __
awareness; complex; awareness; simple
Child with ADHD but it’s a seizure question, diagnosis?
Absence seizures
Face pain, lancinating pain, worse with chewing, diagnosis?
Trigeminal neuralgia
Abort a seizure, tx?
Benzodiazepines
How do you treat Absence?
ethosuximide
Abort status epilepticus, treatment?
IV benzos!!! fosphenytoin, phenobarbital, midazolam and propofol
How do you treat trigeminal neuralgia?
carbamazepine
In which type of seizure do you lose consciousness (2)?
Grand mal seizure, absence
In which type of seizure do you not lose consciousness (2)?
myoclonic (spastic contractions), atonic (loses tone)
Name VITAMINS (causes of seizures)
Vascular (stroke bleed); Infection (encephalitis, meningitis); Trauma (MVA, TBI); Autoimmune (lupus, vasculitis); Metabolic (Na, Ca, Mg, O2, Glucose); Idiopathic /Ingestion/wIthdrawal; Neoplasm (mets v primary); pSychiatric (faking it, iatrogenic)
What’s the treatment for atonic and myoclonic seizures?
valproate (and helmets for atonic)
No tremor at rest that arises with movement, diagnosis?
Essential tremor
How do you treat essential tremor?
Propranolol
Tremor that gets worse the closer to the target you get, diagnosis?
Cerebellar lesion (CVA, EtOH)
How do you treat Parkinson’s in a pt that is functional or less than 70?
Ropirinole or pramipexole (not bromocriptine)
How do you treat Parkinsons in a pt that is greater than 70 or non functional?
levidopa-carbidopa
HTN, tachycardia, hallucinations, diaphoresis, tremor, diganosis?
Delirium tremens
How do you treat delirium tremens?
Benzos (lorazepam prn tx; oxazepam or chlordiazepoxide (ppx))
How does carbidopa work?
prevents break down of L-dopa in to dopamine in the periphery
Lacrimation, ptosis, conjunctival injection, what type of HA?
Cluster (comes in clusters!)
Who cannot get triptans for migraines?
people with CAD
Photophobia, phonophobia, unilateral pounding headache, diagnosis?
Migraine
Young female on oral contraceptive with symptoms of a brain tumor, dx?
Benign intracranial hypertension (aka pseudotumor cerebri)
Abort cluster headaches, tx?
Oxygen
Prophylaxis against cluster headaches, tx?
verapamil
Abort migraines, tx?
Ergots or triptans
Prophylaxis against migraines?
Propranolol
How do you diagnose benign intracranial HTN?
CT scan first (rule out tumor), LP relieves symptoms
Vice like pain that radiates to the neck, diagnosis?
Tension headache
Which primary headaches are unilateral? bilateral?
cluster and migraine are unilateral
tension is bilateral
Tx of benign intracranial HTN (3)
first line: acetazolamide (also stop OCPs)
then serial LPs or VP shunt if necessary
Name 5 causes of 2ndary headaches?
hemorrhage, tumor, abscess, meningitis, IIH (idiopathic intracranial htn)
History of cancer and back pain, diagnosis?
Mets
Lightning pain down the leg of a young pt doing heavy lifting, diagnosis?
Disc herniation
History of trauma and upper motor neuro lesions in the spine, diagnosis?
Fracture, cord transection
Really old lady has back pain with tenderness on her spine, diagnosis and next step?
Compression fracture, start with xray
Back pain and sexual dysfunction, bowel and bladder dysfunction, diagnosis?
Cord compression
Belt like pain around the lumbosacral region, diagnosis?
Musculoskeletal
Lightning pain down the leg of an old guy without heavy lifting, diagnosis?
Osteophytes
Best tx for musculoskeletal back pain?
NSAIDs and Stretches (not rest)
Claudication of the buttocks that is better going up stairs, diagnosis?
Spinal stenosis
Saddle anesthesia, diagnosis and what’s the next step?
Cord compression, steroids first, then MRI (then disease specific - drain hematoma, I&D/antibx for abscess, surgery/radiation for tumor, surgery for fracture)
Elderly person who has a slowly progressive dementia after a fall, diagnosis?
Subdural
Parkinson’s and dementia, diagnosis?
Lewy Body dementia
Young person with rapid onset dementia and myoclonus, diagnosis?
prion disease (CJD)
Elderly person who has a slowly progressive dementia after the death of their spouse, dx?
Pseudodementia (depression)
Dementia and a couple of strokes, diagnosis?
Vascular dementia
Loss of short term memory, but long term memory and social graces spared - dx?
Alzheimers (long term comes later)
Elderly man who is hyper sexual and foul mouthed when he wasn’t before - diagnosis?
Pick’s disease (frontotemporal dementia)
Name 5 causes of reversible dementia (there are likely more)
1) B12 deficiency; 2) syphilis; 3) hypothyroid; 4) CKD; 5) depression
What tests should you get to rule out reversible causes of dementia (5)?
1) B12 level, 2) RPR, 3) TSH and T4, 4) BUN/Cr
5) CT scan and MRI
Treatment for Meniere’s?
Diuretic and low salt diet
Vertigo with ataxia, dx and next step?
Central vertigo, get an MRI
vertigo with a focal neurologic deficit
Rotary Nystagmus, dx?
BPPV
Treatment for BPPV
Otolith removal = Epley maneuver
How do you diagnose BPPV?
Dix Hallpike shows rotary nystagmus (and history!)
Vertigo + tinnitus or hearing loss = ? (not Meniere)
Peripheral vertigo
What is the triad of Meniere’s? How long do episodes last?
tinnitus, hearing loss, episodic vertigo; greater than 30 mins less than one hour
Which one is associated with hearing loss, labyrinthitis or vestibular neuritis? How do they present
labyrinthitis; vertigo, nausea/vom, tinnitus, hearing loss (specifically labyrinthitis)
What causes labyrinthitis/vestibular neuritis?
post-viral syndrome (usually URI) (usually presents weeks after URI with vertigo, nausea/vom, tinnitus, hearing loss (specifically labyrinthitis)
How do you diagnose brain death?
2 physicians individually assess brainstem reflexes as absent, spontaneous breathing trial
Locked in syndrome is a stroke of what?
Basilar artery (pontine stroke)
No cerebral function, but has eye opening, sleep/wake cycles, and breathes, diagnosis?
Persistent vegetative state (they won’t come back from this - they have no cerebral function)
In coma pt has decreased __ function (can come back), and __ are intact.
cerebral (depressed level of consciousness); brain stem reflexes