Neurology Flashcards

1
Q

In the human body, the endocrine system has ______ control over the human body, where as the nervous system has ____ control.

A

Slow

Fast

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2
Q

What does the CNS consist of?

A

Brain

Spinal Cord

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3
Q

What does the PNS consist of?

A

Nerves that connect the brain or spinal cord with the body’s muscles, glands, and sense organs.

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4
Q

How do axons get their “supplies”?

A

“Supplies” move DOWN the axon and back UP the axon using moving proteins

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5
Q

Neurons are ______, which means they do not divide.

A

Amitotic

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6
Q

Neurons have a ____ ____ metabolic rate, meaning they need a lot of _______ and have a lot of ________.

A

Very High

Glucose

Mitochondria

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7
Q

T/F: Neurons are the most numerous cell in the CNS

A

False (Glial cells are)

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8
Q

This type of glial cell works in healing, ion concentration regulation, synapse formation, and creates a framework for neurons.

A

Astrocytes

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9
Q

This type of glial cells form and maintain myelin in the CNS.

A

Oligodendrocytes

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10
Q

This type of glial cells are important “workers” in the immune system.

A

Microglia (CNS Macrophages)

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11
Q

This type of glial cell creates CSF in the CNS.

A

Ependymal cells

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12
Q

This type of glial cells create myelin in the PNS.

A

Schwann Cells

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13
Q

Are afferent neurons in the CNS, PNS, or Both?

A

Afferent neurons cell body and long peripheral process are in the PNS while the central process of the axon is in the CNS

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14
Q

Are efferent neurons in the CNS, PNS, or Both?

A

The cell body, dendrites, and a small amount of the axon are in the CNS, while most of the axon is in the PNS

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15
Q

Are interneurons in the CNS, PNS, or Both?

A

Inter neurons are entirely in the CNS.

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16
Q

Interneurons account for ____% of all neurons.

A

> 99

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17
Q

Afferent nerves get ______ by a stimulus;

Efferent nerves cause an _______.

A

affected

effect

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18
Q

T/F: peripheral portions of nerves can sometimes regenerate a bit because of their Schwann Cells

A

True

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19
Q

T/F: Completely CNS neurons can also regenerate

A

False (Completely CNS neuron can not regenerate at all)

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20
Q

axons are severed, they can repair themselves and restore significant function only if the damage occurs _______ the central nervous system

A

Outside

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21
Q

axon regrowth proceeds at a rate of only ___ mm per day.

A

1

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22
Q

Charge is more ______ outside the cell. Charge is more ______ inside the cell. What is this called?

A

positive

negative

RMP

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23
Q

Describe the function of the Na+/K+ pump

A

It is an active transport pump that uses ATP to transport 3 Na+ (Against the concentration gradient) outside of the cell and 2 K+ (Against the concentration gradient) into the cell creating a negative resting cell membrane (negative interior).

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24
Q

What would happen to the RMP if there was no ATP to run the Na+/K+ pump?

A

It would create a less negative RMP. (Na+ can still enter the cell through Facilitated diffusion, and K+ can still leave the cell through Facilitated diffusion)

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25
This is the potential moving from RMP to less negative values.
Depolarization
26
This is the potential moving back to the RMP
Repolarization
27
This is the potential moving away from the RMP in a more negative direction.
Hyperpolarization
28
Threshold can be reached when there are more ______ than ______.
EPSPs > IPSPs
29
What do lidocaine, procaine, marcaine, and tetrotoxin do in regards to the action potential?
They block voltage-gated Na+ channels, prevents an action potential. Without an action potential nerves can not send "signals".
30
T/F: Another action potential can be sent during the absolute refractory period of "a nerve signal".
False (it can not be sent)
31
During the relative refractory period of "a nerve signal". another action potential can be sent, BUT it needs be ________ to over come _________.
bigger hyperpolarization
32
Action potential occurs at the _____ __ _______.
Nodes of Ranvier
33
Action potentials jump from one node to the next as they propagate along a myelinated fiber is known as ________ _________.
Saltatory conduction
34
What THREE things do myelin do?
1. Add speed to nerve signaling 2. Reduce metabolic cost 3. Save room in the nervous system (allows for axons to be thinner)
35
Synapses can pass information ______ or ________ and can be ________ or _________.
Chemically Electrically Inhibitory Excitatory
36
What do synapses use?
Neurotransmitters
37
Pre- and post-synaptic cells are connected by ___ ______ when the signal is electrical.
gap-junctions
38
Autoregulation of a synapse is a _________ feedback loop and a type of _______ signalling.
Negative Autocrine
39
This neurotransmitter is ALWAYS the first signaler on efferent pathways to the peripheral nervous system.
Acetylcholine
40
This neurotransmitter (often nurepinephrine, epinephrine) is important in the SNS and once they're released into the synapses\ they are either taken back up in the pre-synaptic cell or destroyed.
Catecholamine
41
This neurotransmitter is slower than others, acts as a modulator, and is always released with another neurotransmitter.
Serotonin
42
Serotonin is ______ in muscle pathways and _____ in sensory pathways.
Excitatory | Inhibitory
43
This neurotransmittor is made in the cell body and transported down the axon for release.
Endogenous Opiods
44
Endogenous opiods have an effect on what three things?
Appetite, Mood, Emotion
45
Work through the mechanism of tetanus.
Tetanus inhibits GABA (which typically inhibits muscle contraction), so you developed muscle spasms
46
Work through the mechanism of Botulism.
Boutlism interferes with the actions of SNARE proteins at the excitatory synpases in active muscles, SO you develop muscle paralysis
47
What two divisions do the peripheral nervous system consist of?
Afferent (Somatic, Visceral, Special Sensory) Efferent (Somatic and Autonomic Motor)
48
The forebrain consists of these two structures.
Cerebrum | Diencephalon
49
This portion of the brain consists of right and left hemispheres + other structures on the underside of the brain.
Cerebrum
50
The _______ helps connect the right/left hemispheres of the cerebrum.
Dienchephalon
51
Each hemisphere of the cerebrum has a _____ ______.
Cerebral cortex
52
What composes the white matter of the cerebral cortex? What composes the gray matter?
White matter: Myelinatation of the axon Grey matter: Cell bodies
53
What is the primary function of the cerebral cortex?
Integration and processing of afferent information to create an effect on the motor and/or endocrine systems.
54
The left and right cerebral hemispheres are connected by the _____ ______.
Corpus Callosum
55
What are the FOUR lobes of the cerebral cortex?
1. Frontal 2. Parietal 3. Occipital 4. Temporal
56
The folds in the cerebral cortex increase what?
Surface area
57
What are the primary functions of the frontal lobe?
Reasoning Planning Movement
58
What are the primary functions of the parietal lobe?
Movement | Perception of stimuli
59
What are the primary function of the Occipital lobe?
Visual processing
60
What are the primary functions of the temporal lobe?
Perception/Recognition of auditory stimuli | Memory
61
These direct voluntary movements and integrate signals to create many involuntary muscle activities.
Upper motor neurons (IN THE BRAIN)
62
These neurons actually go into a muscle cell and its cell body in the spinal cord and its axon in the periphery.
Lower motor neurons
63
What are the subcortical nuclei?
Areas of gray matter that lie deep within the cerebral hemispheres.
64
What is the primary function of the subcortical nuclei?
Bring information into the cerebrum, carry information out, and connect different areas within a hemisphere.
65
Subcortical nuclei play an important role in
controlling movement, posture and the complex aspects of behavior.
66
What THREE things are contained in the Diencephalon?
Thalamus Hypothalamus Epithalamus
67
What is the key role of the Thalamus?
Arousal and in focusing attention
68
What is the primary role of the hypothalamus?
Master command center for the neural-endocrine coordination
69
Which gland is contained in the epithalamus? What is the role of this?
Pineal Gland (Biological rhythm regulation)
70
This system is a “coalition” of forebrain areas (parts of cerebrum, thalamus, and hypothal) which coordinates emotional centers and and endocrine signals.
Limbic System
71
Where do afferent nerve fibers/"signals" enter the spinal cord? Where do efferent nerve fibers/"signal" leave the spinal cord?
Dorsally Ventrally (REMEMBER: IN through the back, OUT through the front)
72
In the peripheral nervous system, the somatic division can only lead to muscle _________.
Excitation
73
In the peripheral nervous system, the autonomic division can be either _______ or _______.
Excitatory Inhibitory